Dr Russell Pickford

russell pic

Senior Research Fellow and Team Leader - Small Molecule Mass Spectrometry

Facility:
Bioanalytical Mass Spectrometry Facility
Category: Academic Staff
Research profile: Click to view

Biography

2003-2006 PostDoc, biological mass spectrometry, BMSF, UNSW

2007-2008 Mass Spectrometry Applications Specialist, ThermoFisher Scientific, Australia and NZ

2008-2010 Team Leader, BMSF, UNSW

2010-2011 Lecturer in Mass Spectrometry, University of Western Sydney

2011-2018 Research Fellow (Mass Spectrometry), BMSF, UNSW

2018 - current Senior Research Fellow (Mass Spectrometry), BMSF, UNSW

My Research Activities

  • The advancement of mass spectrometric techniques and their application to the solution of complex biological problems, particularly applied to the analysis of small molecules and metabolites
  • development of methods for metabolite profiling (metabolomics and lipidomics)
  • methods for targeted (quantitative) metabolite analysis for specific applications
  • development of LC and sample preparation procedures to facilitate the MS analysis of small molecules in biological fluids and tissues
  • application of modern mass spectrometric methods and incorporation of new advances in mass spectrometry into our laboratory.

Publications

Book Chapters

Pickford R, 2018, 'Mass spectrometry-based metabolomic analysis', in Encyclopedia of Bioinformatics and Computational Biology: ABC of Bioinformatics, pp. 410 - 425, http://dx.doi.org/10.1016/B978-0-12-809633-8.20252-5
Lim XY; Pickford R; Don AS, 2016, 'Assaying ceramide synthase activity in vitro and in living cells using liquid chromatography-mass spectrometry', in Lipid Signaling Protocols, pp. 11 - 22, http://dx.doi.org/10.1007/978-1-4939-3170-5_2
View more

Conference Abstracts

Shrestha G; Vijay A; Stapleton F; White AJ; Pickford R; Carnt N, 2021, 'Tear metabolites expression in bacterial keratitis: Outcomes of an untargeted approach', Virtual, presented at ARVO, Virtual
Unnikrishnan A; Quynh AVN; Pickford R; Nunez A; Hesson L; Pimanda J, 2017, 'A NOVEL MASS SPECTROMETRY METHOD REVEALS THE INTRACELLULAR PHARMACOKINETICS OF AZACYTIDINE THERAPY IN VIVO', in HAEMATOLOGICA, FERRATA STORTI FOUNDATION, SPAIN, Madrid, Vol. 102, pp. 258 - 259, presented at 22nd Congress of the European-Hematology-Association, SPAIN, Madrid, 22 June 2017 - 25 June 2017
Kim W; Jary E; Pickford R; Bartley L; Piguet O; Hodges J; Halliday G, 2016, 'Alteration in plasma lipids in frontotemporal dementia', in JOURNAL OF NEUROCHEMISTRY, WILEY-BLACKWELL, GERMANY, Munich, Vol. 138, pp. 399 - 400, presented at 10th International Conference on Frontotemporal Dementias, GERMANY, Munich, 31 August 2016 - 02 September 2016, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000382568400455&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Harrison-Tikisci Z; von Jonquieres G; Rowlands B; Klugmann C; Delarue F; Ittner L; Pickford R; Housley G; Rae C; Klugmann M, 2015, 'N-acetylaspartate: genomics, phenomics and metabonomics', in JOURNAL OF NEUROCHEMISTRY, WILEY-BLACKWELL, AUSTRALIA, Cairns, Vol. 134, pp. 141 - 141, presented at 25th Biennial Meeting of the International-Society-for-Neurochemistry Jointly with the 13th Meeting of the Asian-Pacific-Society-for-Neurochemistry in Conjunction with the 35th Meeting of the Australasian-Neuroscience-Society, AUSTRALIA, Cairns, 23 August 2015 - 27 August 2015, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000360206300323&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Conference Papers

Unnikrishnan A; Lim XY; Joshi S; Nunez AC; Vaughan L; Pickford R; Hough S; Davidson S; Fong C; Kenealy M; Hiwase DK; Pasalic L; Mohammed S; Lee L; Passam FH; Spring K; Rebeiro P; Ling S; Fuller S; Presgrave P; Roncolato F; Larsen S; Enjeti AK; Stevenson WS; Tiley C; Campbell PJ; Lemech C; Olivier J; Hertzberg M; Polizzotto MN; Pimanda J, 2019, 'In Vivo Assessment of Intracellular Dynamics Comparing Injection Versus Oral Azacitidine in a Phase IIb Investigator Initiated Clinical Trial', in BLOOD, AMER SOC HEMATOLOGY, FL, Orlando, presented at 61st Annual Meeting and Exposition of the American-Society-of-Hematology (ASH), FL, Orlando, 07 December 2019 - 10 December 2019, http://dx.doi.org/10.1182/blood-2019-123921
Okuda LS; Pickford R; Patel M; Woods T; Brimble M; Rye K-A; Passarelli M, 2017, 'Pyrraline, Argpyrimidine and carboxymethyllysine adducts of advanced glycated apoA-IV do not change the apolipoprotein ability in removing cell cholesterol and inhibiting inflammation in macrophages', in MOLECULAR & CELLULAR PROTEOMICS, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, pp. S26 - S26, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000407623600029&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Yau Y; Shin SC; Bustamante S; Pickford R; Leong R; Wasinger V, 2011, 'Tryptophan metabolome signature differences in inflammatory bowel diseases', in Gastroenterology, Chicago USA, pp. S840 - S840, presented at Digestive Diseases Week, Chicago USA
Fedorow HS; Garner B; Pickford R; Hook JM; Kettle E; Cartwright HR; Double KL; Gerlach M; Riederer P; Halliday GM, 2005, 'Investigations of the lipid component of neuromelanin', in Parkinsonism and Related Disorders, Elsevier Sci Ltd, Kidlington, Oxford, England, pp. 58 - 58, presented at 16th International Congress on Parkinson`s Disease and Related Disorders, Berlin, Germany, 05 June 2005 - 09 June 2005
Fedorow HS; Pickford R; Hook J; Double KL; Halliday GM; Gerlach M; Riederer P; Garner B, 2005, 'Dolichol is the major lipid component of neuromelanin in human substanta nigra', in Parkinsonism and Related Disorders, Elsevier Sci Ltd, Kidlington, Oxford, England, pp. 107 - 107, presented at 16th International Congress on Parkinson`s Disease and Related Disorders, Berlin, Germany, 05 June 2005 - 09 June 2005
Fedorow HS; Pickford R; Hook JM; Double KL; Halliday GM; Gerlach M; Riederer P; Garner B, 2005, 'Identification of the major lipid component of neuromelanin in human dopamine neurons', in Proceedings of Aust Neuroscience Society, Perth, WA, pp. 139 - 139, presented at 25th Annual Meeting of the Australian Neuroscience Society, Perth, WA, 30 January 2005 - 02 February 2005
Vishnumohan S; Pickford R; Smythe GA; Arcot J, 2005, 'A sensitive and selective method for quantification of natural folates in foods using electrospray tandem MS', in Proceedings of the Nutrition Society of Australia, National Society of Australia (NSA), Australia, presented at Nutrition Society of Australia (2005), Melbourne, 30 November 2005 - 03 December 2005
Waterton JC; Middleton BJ; Pickford R; Allott CP; Checkley D; Keith RA, 1999, 'Reduced animal use in efficacy testing in disease models with use of sequential experimental designs', in Balls M; VanZeller AM; Halder ME (eds.), PROGRESS IN THE REDUCTION, REFINEMENT AND REPLACEMENT OF ANIMAL EXPERIMENTATION, ELSEVIER SCIENCE BV, ITALY, BOLOGNA, pp. 737 - 745, presented at 3rd World Congress on Alternatives and Animal Use in the Life Science, ITALY, BOLOGNA, 29 August 1999 - 02 September 1999, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000169797500069&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Conference Posters

Chandra-hioe M; Bucknall MP; Pickford R; Arcot J, 2010, 'The levels of Folic Acid and 5-Methyl Tetra Hydrofolate in Australian fortified bread', Copenhagen, presented at 1st International Vitamin Conference, Copenhagen, 19 May 2010 - 21 May 2010

Journal articles

Fu YH; Pickford R; Galper J; Phan K; Wu P; Li H; Kim YB; Dzamko N; Halliday GM; Kim WS, 2024, 'A protective role of ABCA5 in response to elevated sphingomyelin levels in Parkinson’s disease', npj Parkinson's Disease, 10, http://dx.doi.org/10.1038/s41531-024-00632-2
Shrestha GS; Vijay AK; Stapleton F; White A; Pickford R; Carnt N, 2023, 'Human tear metabolites associated with nucleoside-signalling pathways in bacterial keratitis', Experimental Eye Research, 228, pp. 109409, http://dx.doi.org/10.1016/j.exer.2023.109409
Ackerman Grunfeld D; Jones AM; Sun J; Le ST; Pickford R; Huang Q; Manefield M; Kumar N; Lee MJ; O'Carroll DM, 2023, 'Electrochemical degradation of a C6-perfluoroalkyl substance (PFAS) using a simple activated carbon cathode', Environmental Science: Water Research and Technology, 10, pp. 272 - 287, http://dx.doi.org/10.1039/d3ew00543g
Moles E; Howard CB; Huda P; Karsa M; McCalmont H; Kimpton K; Duly A; Chen Y; Huang Y; Tursky ML; Ma D; Bustamante S; Pickford R; Connerty P; Omari S; Jolly CJ; Joshi S; Shen S; Pimanda JE; Dolnikov A; Cheung LC; Kotecha RS; Norris MD; Haber M; de Bock CE; Somers K; Lock RB; Thurecht KJ; Kavallaris M; Moles Meler E, 2023, 'Delivery of PEGylated liposomal doxorubicin by bispecific antibodies improves treatment in models of high-risk childhood leukemia', Science translational medicine, 15, pp. eabm1262 - eabm1262, http://dx.doi.org/10.1126/scitranslmed.abm1262
Phan K; He Y; Bhatia S; Pickford R; Mcdonald G; Mazumder S; Timmins HC; Hodges JR; Piguet O; Dzamko N; Halliday GM; Kiernan MC; Kim WS, 2023, 'Multiple pathways of lipid dysregulation in amyotrophic lateral sclerosis', Brain Communications, 5, http://dx.doi.org/10.1093/braincomms/fcac340
Abomughaid M; Tay ESE; Pickford R; Malladi C; Read SA; Coorssen JR; Gloss BS; George J; Douglas MW, 2023, 'PEMT Mediates Hepatitis C Virus-Induced Steatosis, Explains Genotype-Specific Phenotypes and Supports Virus Replication', International Journal of Molecular Sciences, 24, http://dx.doi.org/10.3390/ijms24108781
Méndez V; Holland S; Bhardwaj S; McDonald J; Khan S; O'Carroll D; Pickford R; Richards S; O'Farrell C; Coleman N; Lee M; Manefield MJ; Mendez V, 2022, 'Aerobic biotransformation of 6:2 fluorotelomer sulfonate by Dietzia aurantiaca J3 under sulfur-limiting conditions', Science of the Total Environment, 829, pp. 154587, http://dx.doi.org/10.1016/j.scitotenv.2022.154587
Fu Y; He Y; Phan K; Pickford R; Kim YB; Dzamko N; Halliday GM; Kim WS, 2022, 'Sex-specific lipid dysregulation in the Abca7 knockout mouse brain', Brain Communications, 4, http://dx.doi.org/10.1093/braincomms/fcac120
Zheng Z; Deletic A; Toe CY; Amal R; Zhang X; Pickford R; Zhou S; Zhang K, 2022, 'Photo-electrochemical oxidation herbicides removal in stormwater: Degradation mechanism and pathway investigation', Journal of Hazardous Materials, 436, http://dx.doi.org/10.1016/j.jhazmat.2022.129239
Soeriyadi AH; Ongley SE; Kehr JC; Pickford R; Dittmann E; Neilan BA, 2022, 'Tailoring Enzyme Stringency Masks the Multispecificity of a Lyngbyatoxin (Indolactam Alkaloid) Nonribosomal Peptide Synthetase', ChemBioChem, 23, http://dx.doi.org/10.1002/cbic.202100574
Fu YH; He Y; Phan K; Bhatia S; Pickford R; Wu P; Dzamko N; Halliday GM; Kim WS, 2022, 'Increased unsaturated lipids underlie lipid peroxidation in synucleinopathy brain', Acta Neuropathologica Communications, 10, http://dx.doi.org/10.1186/s40478-022-01469-7
Pimanda JE; Thoms JAI; Hampton HR; Davidson S; Joshi S; Sarowar CH; Lim XY; Nunez AC; Kakadia PM; Pickford R; Raftery M; Hough S; Buckland G; Bailey M; Ghodke Y; Absar N; Vaughan L; Pasalic L; Fong CY; Kenealy M; Hiwase D; Stoddart R; Mohammed S; Lee L; Passam FH; Spring K; Skarratt KK; Rebeiro P; Larsen SR; Presgrave P; Stevenson WS; Ling S; Tiley C; Fuller S; Roncolato F; Enjeti AK; Hoenemann D; Lemech C; Bohlander SK; Olivier J; Hertzberg M; Unnikrishnan A; Polizzotto MN, 2022, 'In Vivo Drug Incorporation and Intracellular Dynamics of Injectable Versus Oral Azacytidine: A Phase II Open Label Multicentre Trial', Blood, 140, pp. 6927 - 6929, http://dx.doi.org/10.1182/blood-2022-157634
Galper J; Dean NJ; Pickford R; Lewis SJG; Halliday GM; Kim WS; Dzamko N, 2022, 'Lipid pathway dysfunction is prevalent in patients with Parkinson's disease', Brain, 145, pp. 3472 - 3487, http://dx.doi.org/10.1093/brain/awac176
Dyer CEF; Clarke NE; Nguyen DN; Dilrukshi Herath HMP; Hii SF; Pickford R; Traub RJ; Nery SV, 2022, 'Assessing the efficacy of albendazole against hookworm in Vietnam using quantitative PCR and sodium nitrate flotation', PLoS Neglected Tropical Diseases, 16, http://dx.doi.org/10.1371/journal.pntd.0010767
Liu Y; Thalamuthu A; Mather KA; Crawford J; Ulanova M; Wong MWK; Pickford R; Sachdev PS; Braidy N, 2021, 'Plasma lipidome is dysregulated in Alzheimer’s disease and is associated with disease risk genes', Translational Psychiatry, 11, http://dx.doi.org/10.1038/s41398-021-01362-2
He Y; Phan K; Bhatia S; Pickford R; Fu YH; Yang Y; Hodges JR; Piguet O; Halliday GM; Kim WS, 2021, 'Increased VLCFA-lipids and ELOVL4 underlie neurodegeneration in frontotemporal dementia', Scientific Reports, 11, http://dx.doi.org/10.1038/s41598-021-00870-x
Yadav S; Pickford R; Zammit RA; Ballard JWO, 2021, 'Metabolomics shows the Australian dingo has a unique plasma profile', Scientific Reports, 11, http://dx.doi.org/10.1038/s41598-021-84411-6
Jonkhout N; Cruciani S; Santos Vieira HG; Tran J; Liu H; Liu G; Pickford R; Kaczorowski D; Franco GR; Vauti F; Camacho N; Abedini SS; Najmabadi H; Ribas de Pouplana L; Christ D; Schonrock N; Mattick JS; Novoa EM, 2021, 'Subcellular relocalization and nuclear redistribution of the RNA methyltransferases TRMT1 and TRMT1L upon neuronal activation', RNA Biology, 18, pp. 1905 - 1919, http://dx.doi.org/10.1080/15476286.2021.1881291
Soeriyadi AH; Mazmouz R; Pickford R; Al-Sinawi B; Kellmann R; Pearson LA; Neilan BA, 2021, 'Heterologous Expression of an Unusual Ketosynthase, SxtA, Leads to Production of Saxitoxin Intermediates in Escherichia coli', ChemBioChem, 22, pp. 845 - 849, http://dx.doi.org/10.1002/cbic.202000675
Wotton A; Yeung T; Jennepalli S; Teh ZL; Pickford R; Huang S; Conibeer G; Stride JA; Patterson RJ, 2021, 'Simultaneous Fe3O4Nanoparticle Formation and Catalyst-Driven Hydrothermal Cellulose Degradation', ACS Omega, 6, pp. 10790 - 10800, http://dx.doi.org/10.1021/acsomega.1c00393
Soeriyadi AH; Mazmouz R; Pickford R; Al‐Sinawi B; Kellmann R; Pearson LA; Neilan BA, 2021, 'Cover Feature: Heterologous Expression of an Unusual Ketosynthase, SxtA, Leads to Production of Saxitoxin Intermediates in Escherichia coli (5/2021)', ChemBioChem, 22, pp. 762 - 762, http://dx.doi.org/10.1002/cbic.202100062
Stayte S; Laloli KJ; Rentsch P; Lowth A; Li KM; Pickford R; Vissel B, 2020, 'The kainate receptor antagonist UBP310 but not single deletion of GluK1, GluK2, or GluK3 subunits, inhibits MPTP-induced degeneration in the mouse midbrain', Experimental Neurology, 323, http://dx.doi.org/10.1016/j.expneurol.2019.113062
Ballard B; Yadav S; Pickford R; Zammit R, 2020, 'Metabolomics shows the Australian dingo has a unique plasma profile', bioRxiv, pp. 2020.11.02.364307, http://dx.doi.org/10.1101/2020.11.02.364307
Liew G; Tse B; Ho IV; Joachim N; White A; Pickford R; Maltby D; Gopinath B; Mitchell P; Crossett B, 2020, 'Acylcarnitine abnormalities implicate mitochondrial dysfunction in patients with neovascular age-related macular degeneration', Investigative Ophthalmology and Visual Science, 61, http://dx.doi.org/10.1167/IOVS.61.8.32
Liu Y; Chan DKY; Thalamuthu A; Wen W; Jiang J; Paradise M; Lee T; Crawford J; Wai Kin Wong M; Hua Xu Y; Poljak A; Pickford R; Sachdev PS; Braidy N; Xu Y-H, 2020, 'Plasma lipidomic biomarker analysis reveals distinct lipid changes in vascular dementia', Computational and Structural Biotechnology Journal, 18, pp. 1613 - 1624, http://dx.doi.org/10.1016/j.csbj.2020.06.001
Phan K; He Y; Pickford R; Bhatia S; Katzeff JS; Hodges JR; Piguet O; Halliday GM; Kim WS, 2020, 'Uncovering pathophysiological changes in frontotemporal dementia using serum lipids', Scientific Reports, 10, http://dx.doi.org/10.1038/s41598-020-60457-w
Shimabukuro Okuda L; Tallada Iborra R; Ramos Pinto P; Fabres Machado U; Corrêa-Giannella ML; Pickford R; Woods T; Brimble MA; Rye KA; Passarelli M, 2020, 'Advanced Glycated apoA-IV Loses Its Ability to Prevent the LPS-Induced Reduction in Cholesterol Efflux-Related Gene Expression in Macrophages', Mediators of Inflammation, 2020, http://dx.doi.org/10.1155/2020/6515401
Wong MWK; Thalamuthu A; Braidy N; Mather KA; Liu Y; Ciobanu L; Baune BT; Armstrong NJ; Kwok J; Schofield P; Wright MJ; Ames D; Pickford R; Lee T; Poljak A; Sachdev PS, 2020, 'Genetic and environmental determinants of variation in the plasma lipidome of older australian twins', eLife, 9, pp. 1 - 28, http://dx.doi.org/10.7554/eLife.58954
Wong MWK; Thalamuthu A; Braidy N; Mather K; Liu Y; Ciobanu L; Baune B; Armstrong N; Kwok J; Schofield P; Wright M; Ames D; Pickford R; Lee T; Poljak A; Sachdev P, 2020, 'Genetic and environmental determinants of variation in the plasma lipidome of older Australian twins', , http://dx.doi.org/10.1101/2020.05.05.075606
Wong MWK; Braidy N; Pickford R; Sachdev PS; Poljak A, 2019, 'Comparison of Single Phase and Biphasic Extraction Protocols for Lipidomic Studies Using Human Plasma', Frontiers in Neurology, 10, pp. 1 - 11, http://dx.doi.org/10.3389/fneur.2019.00879
Tetu SG; Sarker I; Schrameyer V; Pickford R; Elbourne LDH; Moore LR; Paulsen IT, 2019, 'Plastic leachates impair growth and oxygen production in Prochlorococcus, the ocean’s most abundant photosynthetic bacteria', Communications Biology, 2, http://dx.doi.org/10.1038/s42003-019-0410-x
Coffey MJ; Nielsen S; Wemheuer B; Kaakoush NO; Garg M; Needham B; Pickford R; Jaffe A; Thomas T; Ooi CY, 2019, 'Gut Microbiota in Children With Cystic Fibrosis: A Taxonomic and Functional Dysbiosis', Scientific Reports, 9, pp. 18593, http://dx.doi.org/10.1038/s41598-019-55028-7
Wong MWK; Braidy N; Pickford R; Vafaee F; Crawford J; Muenchhoff J; Schofield P; Attia J; Brodaty H; Sachdev P; Poljak A, 2019, 'Plasma lipidome variation during the second half of the human lifespan is associated with age and sex but minimally with BMI', PLoS ONE, 14, pp. e0214141, http://dx.doi.org/10.1371/journal.pone.0214141
D'Agostino PM; Woodhouse JN; Liew HT; Sehnal L; Pickford R; Wong HL; Burns BP; Neilan BA, 2019, 'Bioinformatic, phylogenetic and chemical analysis of the UV-absorbing compounds scytonemin and mycosporine-like amino acids from the microbial mat communities of Shark Bay, Australia', Environmental Microbiology, 21, pp. 702 - 715, http://dx.doi.org/10.1111/1462-2920.14517
Wong MWK; Braidy N; Crawford J; Pickford R; Song F; Mather KA; Attia J; Brodaty H; Sachdev P; Poljak A, 2019, 'APOE Genotype Differentially Modulates Plasma Lipids in Healthy Older Individuals, with Relevance to Brain Health', Journal of Alzheimer's Disease, 72, pp. 703 - 716, http://dx.doi.org/10.3233/JAD-190524
von Jonquieres G; Spencer ZHT; Rowlands BD; Klugmann CB; Bongers A; Harasta AE; Parley KE; Cederholm J; Teahan O; Pickford R; Delerue F; Ittner LM; Fröhlich D; McLean CA; Don AS; Schneider M; Housley GD; Rae CD; Klugmann M; Froehlich D, 2018, 'Uncoupling N-acetylaspartate from brain pathology: implications for Canavan disease gene therapy', Acta Neuropathologica, 135, pp. 95 - 113, http://dx.doi.org/10.1007/s00401-017-1784-9
Iborra RT; Machado-Lima A; Okuda LS; Pinto PR; Nakandakare ER; Machado UF; Correa-Giannella ML; Pickford R; Woods T; Brimble MA; Rye KA; Lu R; Yokoyama S; Passarelli M, 2018, 'AGE-albumin enhances ABCA1 degradation by ubiquitin-proteasome and lysosomal pathways in macrophages', Journal of Diabetes and its Complications, 32, pp. 1 - 10, http://dx.doi.org/10.1016/j.jdiacomp.2017.09.012
Unnikrishnan A; Vo ANQ; Pickford R; Raftery MJ; Nunez AC; Verma A; Hesson LB; Pimanda JE, 2018, 'AZA-MS: A novel multiparameter mass spectrometry method to determine the intracellular dynamics of azacitidine therapy in vivo', Leukemia, 32, pp. 900 - 910, http://dx.doi.org/10.1038/leu.2017.340
Kim WS; Jary E; Pickford R; He Y; Ahmed RM; Piguet O; Hodges JR; Halliday GM, 2018, 'Lipidomics analysis of behavioral variant frontotemporal dementia: A scope for biomarker development', Frontiers in Neurology, 9, http://dx.doi.org/10.3389/fneur.2018.00104
Atashrazm F; Hammond D; Perera G; Dobson-Stone C; Mueller N; Pickford R; Kim WS; Kwok JB; Lewis SJG; Halliday GM; Dzamko N, 2018, 'Reduced glucocerebrosidase activity in monocytes from patients with Parkinson’s disease', Scientific Reports, 8, http://dx.doi.org/10.1038/s41598-018-33921-x
Cullen A; D'Agostino PM; Mazmouz R; Pickford R; Wood S; Neilan BA, 2018, 'Insertions within the Saxitoxin Biosynthetic Gene Cluster Result in Differential Toxin Profiles', ACS Chemical Biology, 13, pp. 3107 - 3114, http://dx.doi.org/10.1021/acschembio.8b00608
Aw WC; Towarnicki SG; Melvin RG; Youngson NA; Garvin MR; Hu Y; Nielsen S; Thomas T; Pickford R; Bustamante S; Vila-Sanjurjo A; Smyth GK; Ballard JWO, 2018, 'Genotype to phenotype: Diet-by-mitochondrial DNA haplotype interactions drive metabolic flexibility and organismal fitness', PLoS Genetics, 14, http://dx.doi.org/10.1371/journal.pgen.1007735
Giardina M; Cheong S; Marjo CE; Clode PL; Guagliardo P; Pickford R; Pernice M; Seymour JR; Raina JB, 2018, 'Quantifying inorganic nitrogen assimilation by synechococcus using bulk and single-cell mass spectrometry: A comparative study', Frontiers in Microbiology, 9, pp. 2847, http://dx.doi.org/10.3389/fmicb.2018.02847
Wong MW; Braidy N; Poljak A; Pickford R; Thambisetty M; Sachdev PS, 2017, 'Dysregulation of lipids in Alzheimer's disease and their role as potential biomarkers', Alzheimers Dement, 13, pp. 810 - 827, http://dx.doi.org/10.1016/j.jalz.2017.01.008
da Silva KS; Pinto PR; Fabre NT; Gomes DJ; Thieme K; Okuda LS; Iborra RT; Freitas VG; Shimizu MHM; Teodoro WR; Marie SKN; Woods T; Brimble MA; Pickford R; Rye KA; Okamoto M; Catanozi S; Correa-Giannela ML; Machado UF; Passarelli M, 2017, 'N-acetylcysteine counteracts adipose tissue macrophage infiltration and insulin resistance elicited by advanced glycated albumin in healthy rats', Frontiers in Physiology, 8, pp. 723, http://dx.doi.org/10.3389/fphys.2017.00723
Pereyra JPA; D'Agostino PM; Mazmouz R; Woodhouse JN; Pickford R; Jameson I; Neilan BA, 2017, 'Molecular and morphological survey of saxitoxin-producing cyanobacterium Dolichospermum circinale (Anabaena circinalis) isolated from geographically distinct regions of Australia', Toxicon, 138, pp. 68 - 77, http://dx.doi.org/10.1016/j.toxicon.2017.08.006
Liu T; Mazmouz R; Ongley SE; Chau R; Pickford R; Woodhouse JN; Neilan BA, 2017, 'Directing the Heterologous Production of Specific Cyanobacterial Toxin Variants', ACS Chemical Biology, 12, pp. 2021 - 2029, http://dx.doi.org/10.1021/acschembio.7b00181
Vishnumohan S; Pickford R; Arcot J, 2017, 'Naturally occurring folates in selected traditionally prepared foods in Southern India', Journal of Food Science and Technology, 54, pp. 4173 - 4180, http://dx.doi.org/10.1007/s13197-017-2870-7
Gomes DJ; Velosa AP; Okuda LS; Fusco FB; da Silva KS; Pinto PR; Nakandakare ER; Correa-Giannella ML; Woods T; Brimble MA; Pickford R; Rye KA; Teodoro WR; Catanozi S; Passarelli M, 2016, 'Glycated albumin induces lipid infiltration in mice aorta independently of DM and RAS local modulation by inducing lipid peroxidation and inflammation', Journal of Diabetes and its Complications, 30, pp. 1614 - 1621, http://dx.doi.org/10.1016/j.jdiacomp.2016.07.001
Kaakoush NO; Pickford R; Jaffe A; Ooi CY, 2016, 'Is there a role for stool metabolomics in cystic fibrosis?', Pediatrics International, 58, pp. 808 - 811, http://dx.doi.org/10.1111/ped.13063
Richards SL; Cawley AT; Cavicchioli R; Suann CJ; Pickford R; Raftery MJ, 2016, 'Aptamer based peptide enrichment for quantitative analysis of gonadotropin-releasing hormone by LC-MS/MS', Talanta, 150, pp. 671 - 680, http://dx.doi.org/10.1016/j.talanta.2016.01.006
Katoch M; Mazmouz R; Chau R; Pearson LA; Pickford R; Neilan BA, 2016, 'Heterologous production of cyanobacterial mycosporine-like amino acids mycosporine-ornithine and mycosporine-lysine in Escherichia coli', Applied and Environmental Microbiology, 82, pp. 6167 - 6173, http://dx.doi.org/10.1128/AEM.01632-16
D'Agostino PM; Javalkote VS; Mazmouz R; Pickford R; Puranik PR; Neilan BA, 2016, 'Comparative profiling and discovery of novel glycosylated mycosporine-like amino acids in two strains of the cyanobacterium Scytonema cf. crispum', Applied and Environmental Microbiology, 82, pp. 5951 - 5959, http://dx.doi.org/10.1128/AEM.01633-16
Kashem MA; Ahmed S; Sultana N; Ahmed EU; Pickford R; Rae C; Šerý O; McGregor IS; Balcar VJ, 2016, 'Metabolomics of neurotransmitters and related metabolites in post-mortem tissue from the dorsal and ventral striatum of alcoholic human brain', Neurochemical Research, 41, pp. 385 - 397, http://dx.doi.org/10.1007/s11064-016-1830-3
Hart-Smith G; Yagoub D; Tay AP; Pickford R; Wilkins MR, 2016, 'Large scale mass spectrometry-based identifications of enzyme-mediated protein methylation are subject to high false discovery rates', Molecular and Cellular Proteomics, 15, pp. 989 - 1006, http://dx.doi.org/10.1074/mcp.M115.055384
Toscan CE; Rahimi M; Bhadbhade M; Pickford R; McAlpine SR; Lock RB, 2015, 'Thioimidazoline based compounds reverse glucocorticoid resistance in human acute lymphoblastic leukemia xenografts', Organic and Biomolecular Chemistry, 13, pp. 6299 - 6312, http://dx.doi.org/10.1039/c5ob00779h
Yau YY; Leong RWL; Shin S; Bustamante S; Pickford R; Hejazi L; Campbell B; Wasinger VC, 2014, 'Bimodal plasma metabolomics strategy identifies novel inflammatory metabolites in inflammatory bowel diseases', Discovery Medicine, 18, pp. 113 - 124
Couttas TA; Kain N; Daniels B; Lim XY; Shepherd C; Kril J; Pickford R; Li H; Garner B; Don AS, 2014, 'Loss of the neuroprotective factor Sphingosine 1-phosphate early in Alzheimer's disease pathogenesis', Acta Neuropathologica Communications, 2, http://dx.doi.org/10.1186/2051-5960-2-9
Liu J; Pickford R; Meagher AP; Ward RL, 2011, 'Quantitative analysis of tissue folate using ultra-high performance liquid chromatography tandem mass spectrometry', Analytical Biochemistry, 411, pp. 210 - 217, http://dx.doi.org/10.1016/j.ab.2010.12.033
Yau Y; Shin SS; Bustamante S; Pickford R; Leong RW; Wasinger VC, 2011, 'Tryptophan Metabolome Signature Differences in Inflammatory Bowel Diseases', Gastroenterology, 140, pp. S - 840, http://dx.doi.org/10.1016/s0016-5085(11)63487-2
dos Remedios CG; Estigoy C; Cameron D; Ho JWK; Herbert B; Padula M; Pickford R; Guilhaus M; Odeberg J; Ponten F, 2010, 'Proteomics of the Human Cardiac Intercalated Disc: A More Complex Multi-Functional Structure than was Previously Thought', Biophysical Journal, 98, pp. 755a - 756a
Bustamante S; Pickford R; Shin S; Luber R; Campbell B; Redmond D; Yau Y; Leong RWL; Wasinger V, 2010, 'Metabolomics in inflammatory bowel disease', JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 25, pp. A83 - A83, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000283321200226&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Rodrigues JA; Taylor AM; Sumpton DP; Reynolds JC; Pickford R; Thomas‐Oates J, 2009, 'ChemInform Abstract: Mass Spectrometry of Carbohydrates: Newer Aspects', ChemInform, 40, http://dx.doi.org/10.1002/chin.200908280
Kellmann R; Mihali TK; Jae jeon Y; Pickford R; Pomati F; Neilan BA, 2008, 'Biosynthetic intermediate analysis and functional homology reveal a saxitoxin gene cluster in cyanobacteria', Applied and Environmental Microbiology, 74, pp. 4044 - 4053, http://dx.doi.org/10.1128/AEM.00353-08
Gruendling T; Pickford R; Guilhaus M; Barner-Kowollik CW, 2008, 'Degradation of RAFT Polymers in a Cyclic Ether Studied via High Resolution ESI-MS: Implications for Synthesis, Storage, and End-Group Modification', Journal of Polymer Science Part A - Polymer Chemistry, 46, pp. 7447 - 7461
Rodrigues JA; Taylor AM; Sumpton DP; Reynolds JC; Pickford R; Thomas-Oates J, 2007, 'Mass Spectrometry of Carbohydrates: Newer Aspects', Advances in Carbohydrate Chemistry and Biochemistry, 61, pp. 59 - 141, http://dx.doi.org/10.1016/S0065-2318(07)61003-8
Fedorow HS; Pickford R; Kettle E; Cartwright M; Halliday GM; Gerlach M; Riederer P; Garner B; Double KL, 2006, 'Investigation of the lipid component of neuromelanin', Journal of Neural Transmission, 113, pp. 735 - 739
Fedorow HS; Pickford R; Hook JM; Double KL; Halliday GM; Gerlach M; Riederer P; Garner B, 2005, 'Dolichol is the major lipid component of human substantia nigra neuromelanin', Journal of Neurochemistry, 92, pp. 990 - 995
Kuiper I; Lagendijk EL; Pickford R; Derrick JP; Lamers GEM; Thomas-Oates JE; Lugtenberg BJJ; Bloemberg GV, 2004, 'Characterization of two Pseudomonas putida lipopeptide biosurfactants, putisolvin I and II, which inhibit biofilm formation and break down existing biofilms', Molecular Microbiology, 51, pp. 97 - 113, http://dx.doi.org/10.1046/j.1365-2958.2003.03751.x
White IR; Pickford R; Wood J; Skehel JM; Gangadharan B; Cutler P, 2004, 'A statistical comparison of silver and SYPRO Ruby staining for proteomic analysis', Electrophoresis, 25, pp. 3048 - 3054, http://dx.doi.org/10.1002/elps.200405947
Hansen HR; Pickford R; Thomas-Oates J; Jaspars M; Feldmann J, 2004, '2-Dimethylarsinothioyl Acetic Acid Identified in a Biological Sample: The First Occurrence of a Mammalian Arsinothioyl Metabolite', Angewandte Chemie - International Edition, 43, pp. 337 - 340, http://dx.doi.org/10.1002/anie.200352740
Hansen HR; Pickford R; Thomas‐Oates J; Jaspars M; Feldmann J, 2004, '2‐Dimethylarsinothioyl Acetic Acid Identified in a Biological Sample: The First Occurrence of a Mammalian Arsinothioyl Metabolite', Angewandte Chemie, 116, pp. 341 - 344, http://dx.doi.org/10.1002/ange.200352740
Miguens-Rodriguez M; Pickford R; Thomas-Oates JE; Pergantis SA, 2002, 'Arsenosugar identification in seaweed extracts using high-performance liquid chromatography/electrospray ion trap mass spectrometry', Rapid Communications in Mass Spectrometry, 16, pp. 323 - 331, http://dx.doi.org/10.1002/rcm.578
Pickford R; Miguens-Rodriguez M; Afzaal S; Speir P; Pergantis SA; Thomas-Oates JE, 2002, 'Application of the high mass accuracy capabilities of FT-ICR-MS and Q-ToF-MS to the characterisation of arsenic compounds in complex biological matrices', Journal of Analytical Atomic Spectrometry, 17, pp. 173 - 176, http://dx.doi.org/10.1039/b109842j
Cutler P; Bell DJ; Birrell HC; Connelly JC; Connor SC; Holmes E; Mitchell BC; Monté SY; Neville BA; Pickford R; Polley S; Schneider K; Skehel JM, 1999, 'An integrated proteomic approach to studying glomerular nephrotoxicity', Electrophoresis, 20, pp. 3647 - 3658, http://dx.doi.org/10.1002/(sici)1522-2683(19991201)20:18<3647::aid-elps3647>3.0.co;2-%23

Preprints

Shrestha GS; Vijay AK; Stapleton F; Pickford R; Carnt N, 2021, Human Tear Metabolomics Using Liquid Chromatography-Q Exactive-HF Mass Spectrometry, , http://dx.doi.org/10.1101/2021.01.18.424378
Jonkhout N; Cruciani S; Vieira HGS; Tran J; Liu H; Liu G; Pickford R; Kaczorowski D; Franco G; Vauti F; Camacho N; Abedini SS; Najmabadi H; de Pouplana LR; Christ D; Schonrock N; Mattick J; Novoa EM, 2020, Subcellular relocalization and nuclear redistribution of the RNA methyltransferases TRMT1 and TRMT1L upon neuronal activation, , http://dx.doi.org/10.1101/2020.10.17.343772
Grunfeld DA; Jones AM; Sun J; Le ST; Pickford R; Huang Q; Manefield M; Kumar N; Lee M; O’Carroll D, Electrochemical Degradation of a Perfluoroalkyl Substance (Pfas) Using a Simple Activated Carbon Cathode, , http://dx.doi.org/10.2139/ssrn.4203122
View less

Location

2101, Level 2, Biological Sciences (Building E26)

Contact

+61410761718
+61410761718
+61 2 8214 6831
logo unsw

Study

Study

Research

Research

About

About

Contact

Contact

Authorised by the Executive Director of Mark Wainwright Analytical Centre, UNSW CRICOS Provider Code 00098G, ABN 57 195 873 179

Mark Wainwright Analytical Centre, UNSW, Sydney, NSW, 2052, Australia | Email: analytical@unsw.edu.au