Dr Alex Macmillan



Book Chapters

Carnell M;Macmillan A;Whan R, 2014, 'Fluorescence recovery after photobleaching (FRAP): Acquisition, analysis, and applications', in Methods in Membrane Lipids: Second Edition, pp. 255 - 271, http://dx.doi.org/10.1007/978-1-4939-1752-5_18
Macmillan A;Cranfield CG;Martinac B, 2014, 'Fluorescence methods for monitoring mechanosensitive channels', in Handbook of Imaging in Biological Mechanics, pp. 425 - 431, http://dx.doi.org/10.1201/b17566
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Conference Papers

Karolin J;Pánek D;MacMillan A;Rolinski O;Birch D, 2009, 'Fluorescence biosensing in nanopores', in Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009, pp. 4154 - 4157, http://dx.doi.org/10.1109/IEMBS.2009.5333940
Macmillan AM;McGuinness CD;Sagoo K;McLoskey D;Pickup JC;Birch DJ S, 2008, 'Effect of pH on aqueous phenylalanine studied using a 265-nm pulsed light-emitting diode', in Annals of the New York Academy of Sciences, pp. 300 - 304, http://dx.doi.org/10.1196/annals.1430.056
Sutter JU;Macmillan AM;Birch DJ S;Rolinski OJ, 2008, 'Toward single-metal-ion sensing by Förster resonance energy transfer', in Annals of the New York Academy of Sciences, pp. 62 - 67, http://dx.doi.org/10.1196/annals.1430.037

Journal articles

Cao C;Zhao J;Chen F;Lu M;Khine YY;Macmillan A;Garvey CJ;Stenzel MH, 2018, 'Drug-Induced Morphology Transition of Self-Assembled Glycopolymers: Insight into the Drug-Polymer Interaction', Chemistry of Materials, vol. 30, pp. 5227 - 5236, http://dx.doi.org/10.1021/acs.chemmater.8b01882
Yasarapudi VB;Frazer L;Davis NJ L K;Booker EP;Macmillan A;Gallaher JK;Roberts D;Perrier S;Schmidt TW, 2018, 'Optimization of energy transfer in a polymer composite with perylene chromophores', Journal of Materials Chemistry C, vol. 6, pp. 7333 - 7342, http://dx.doi.org/10.1039/c8tc02457j
Yasarapudi VB;Frazer L;Webb JE A;Gallaher JK;MacMillan A;Falber A;Thordarson P;Schmidt TW, 2018, 'Competing Energy Transfer Pathways in a Five-Chromophore Perylene Array', Journal of Physical Chemistry C, vol. 122, pp. 13937 - 13943, http://dx.doi.org/10.1021/acs.jpcc.8b01084
Sagnella SM;Trieu J;Brahmbhatt H;MacDiarmid JA;MacMillan A;Whan RM;Fife CM;McCarroll JA;Gifford AJ;Ziegler DS;Kavallaris M, 2018, 'Targeted doxorubicin-loaded bacterially derived nano-cells for the treatment of neuroblastoma', Molecular Cancer Therapeutics, vol. 17, pp. 1012 - 1023, http://dx.doi.org/10.1158/1535-7163.MCT-17-0738
Chua SW;Cornejo A;Van Eersel J;Stevens CH;Vaca I;Cueto M;Kassiou M;Gladbach A;Macmillan A;Lewis L;Whan R;Ittner LM, 2017, 'The Polyphenol Altenusin Inhibits in Vitro Fibrillization of Tau and Reduces Induced Tau Pathology in Primary Neurons', ACS Chemical Neuroscience, vol. 8, pp. 743 - 751, http://dx.doi.org/10.1021/acschemneuro.6b00433
Chandrakanthan V;Yeola A;Kwan JC;Oliver RA;Qiao Q;Kang YC;Zarzour P;Beck D;Boelen L;Unnikrishnan A;Villanueva JE;Nunez AC;Knezevic K;Palu C;Nasrallah R;Carnell M;Macmillan A;Whan R;Yu Y;Hardy P;Grey ST;Gladbach A;Delerue F;Ittner L;Mobbs R;Walkley CR;Purton LE;Ward RL;Wong JW H;Hesson LB;Walsh W;Pimanda JE, 2016, 'Pdgf-ab and 5-Azacytidine induce conversion of somatic cells into tissue-regenerative multipotent stem cells', Proceedings of the National Academy of Sciences of the United States of America, vol. 113, pp. E2306 - E2315, http://dx.doi.org/10.1073/pnas.1518244113
Constantine M;Liew CK;Lo V;MacMillan A;Cranfield CG;Sunde M;Whan R;Graham RM;Martinac B, 2016, 'Heterologously-expressed and Liposome-reconstituted Human Transient Receptor Potential Melastatin 4 Channel (TRPM4) is a Functional Tetramer', Scientific Reports, vol. 6, http://dx.doi.org/10.1038/srep19352
Ittner A;Chua SW;Bertz J;Volkerling A;Van Der Hoven J;Gladbach A;Przybyla M;Bi M;Van Hummel A;Stevens CH;Ippati S;Suh LS;Macmillan A;Sutherland G;Kril JJ;Silva AP G;Mackay J;Poljak A;Delerue F;Ke YD;Ittner LM, 2016, 'Site-specific phosphorylation of tau inhibits amyloid-β toxicity in Alzheimer's mice', Science, vol. 354, pp. 904 - 908, http://dx.doi.org/10.1126/science.aah6205
Yaffe Y;Hugger I;Yassaf IN;Shepshelovitch J;Sklan EH;Elkabetz Y;Yeheskel A;Pasmanik-Chor M;Benzing C;Macmillan A;Gaus K;Eshed-Eisenbach Y;Peles E;Hirschberg K, 2015, 'The myelin proteolipid plasmolipin forms oligomers and induces liquid-ordered membranes in the Golgi complex', Journal of Cell Science, vol. 128, pp. 2293 - 2302, http://dx.doi.org/10.1242/jcs.166249
Pasquier E;Tuset MP;Sinnappan S;Carnell M;Macmillan A;Kavallaris M, 2015, 'γ-Actin plays a key role in endothelial cell motility and neovessel maintenance', Vascular Cell, vol. 7, http://dx.doi.org/10.1186/s13221-014-0027-2
Carnell M;Macmillan A;Whan R, 2015, 'Fluorescence recovery after photobleaching (FRAP): Acquisition, analysis, and applications', Methods in Molecular Biology, vol. 1232, pp. 255 - 271, http://dx.doi.org/10.1007/978-1-4939-1752-5_18
Sevimli S;Sagnella S;Macmillan A;Whan R;Kavallaris M;Bulmus V;Davis TP, 2015, 'The endocytic pathway and therapeutic efficiency of doxorubicin conjugated cholesterol-derived polymers', Biomaterials Science, vol. 3, pp. 323 - 335, http://dx.doi.org/10.1039/c4bm00224e
Li Y;Duong HT T;Laurent S;Macmillan A;Whan RM;Elst LV;Muller RN;Hu J;Lowe A;Boyer C;Davis TP, 2015, 'Nanoparticles based on star polymers as theranostic vectors: Endosomal-triggered drug release combined with mri sensitivity', Advanced Healthcare Materials, vol. 4, pp. 148 - 156, http://dx.doi.org/10.1002/adhm.201400164
Chang T;Lord MS;Bergmann B;MacMillan A;Stenzel MH, 2014, 'Size effects of self-assembled block copolymer spherical micelles and vesicles on cellular uptake in human colon carcinoma cells', Journal of Materials Chemistry B, vol. 2, pp. 2883 - 2891, http://dx.doi.org/10.1039/c3tb21751e
Sagnella SM;Duong H;Macmillan A;Boyer C;Whan R;McCarroll JA;Davis TP;Kavallaris M, 2014, 'Dextran-based doxorubicin nanocarriers with improved tumor penetration', Biomacromolecules, vol. 15, pp. 262 - 275, http://dx.doi.org/10.1021/bm401526d
Salvemini IL;Gau DM;Reid J;Bagatolli LA;Macmillan A;Moens PD J, 2014, 'Low PIP2 molar fractions induce nanometer size clustering in giant unilamellar vesicles', Chemistry and Physics of Lipids, vol. 177, pp. 51 - 63, http://dx.doi.org/10.1016/j.chemphyslip.2013.11.003
Dunn AE;Dunn DJ;Macmillan A;Whan R;Stait-Gardner T;Price WS;Lim M;Boyer C, 2014, 'Spatial and temporal control of drug release through pH and alternating magnetic field induced breakage of Schiff base bonds', Polymer Chemistry, vol. 5, pp. 3311 - 3315, http://dx.doi.org/10.1039/c4py00150h
Basuki JS;Duong HT T;Macmillan A;Erlich RB;Esser L;Akerfeldt MC;Whan RM;Kavallaris M;Boyer C;Davis TP, 2013, 'Using fluorescence lifetime imaging microscopy to monitor theranostic nanoparticle uptake and intracellular doxorubicin release', ACS Nano, vol. 7, pp. 10175 - 10189, http://dx.doi.org/10.1021/nn404407g
Basuki JS;Duong HT T;MacMillan A;Whan R;Boyer C;Davis TP, 2013, 'Polymer-grafted, nonfouling, magnetic nanoparticles designed to selectively store and release molecules via ionic interactions', Macromolecules, vol. 46, pp. 7043 - 7054, http://dx.doi.org/10.1021/ma401171d
Duong HT T;Hughes F;Sagnella S;Kavallaris M;MacMillan A;Whan R;Hook J;Davis TP;Boyer C, 2012, 'Functionalizing biodegradable dextran scaffolds using living radical polymerization: New versatile nanoparticles for the delivery of therapeutic molecules', Molecular Pharmaceutics, vol. 9, pp. 3046 - 3061, http://dx.doi.org/10.1021/mp300144y
Nomura T;Cranfield CG;Deplazes E;Owen DM;Macmillan A;Battle AR;Constantine M;Sokabe M;Martinac B, 2012, 'Differential effects of lipids and lyso-lipids on the mechanosensitivity of the mechanosensitive channels MscL and MscS', Proceedings of the National Academy of Sciences of the United States of America, vol. 109, pp. 8770 - 8775, http://dx.doi.org/10.1073/pnas.1200051109
MacMillan AM;Panek D;McGuinness CD;Pickup JC;Graham D;Smith WE;Birch DJ S;Karolin J, 2009, 'Improved biocompatibility of protein encapsulation in sol-gel materials', Journal of Sol-Gel Science and Technology, vol. 49, pp. 380 - 384, http://dx.doi.org/10.1007/s10971-008-1883-0
Karolin J;Pánek D;MacMillan A;Rolinski O;Birch D, 2009, 'Fluorescence biosensing in nanopores.', Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference, pp. 4154 - 4157
McGuinness CD;MacMillan AM;Karolin J;Smith WE;Graham D;Pickup JC;Birch DJ S, 2007, 'Single molecule level detection of allophycocyanin by surface enhanced resonance Raman scattering', Analyst, vol. 132, pp. 633 - 634, http://dx.doi.org/10.1039/b706409h
McGuinness CD;Macmillan AM;Sagoo K;McLoskey D;Birch DJ S, 2006, 'Excitation of fluorescence decay using a 265 nm pulsed light-emitting diode: Evidence for aqueous phenylalanine rotamers', Applied Physics Letters, vol. 89, http://dx.doi.org/10.1063/1.2245441
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LG12, Lower Ground, Lowy Cancer Research Centre C25


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