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Bruker BioSpec Avance III 94/20 Preclinical MRI

The MRI facility at the UNSW’s BRIL is one of the most powerful small-animal MRIs in Australia and is able to provide users with state-of-the-art small animal and sample imaging, and MRI biomarker assessment. As part of the National Imaging Facility the scanner can be accessed by researchers from institutions from all over the country.

Bruker Catalyst AFM

The Bruker BioScope Catalyst™ Atomic Force Microscope (AFM) system can provide high resolution (nm) topographical data of biological systems such as living cells. The instrument works in tandem with an inverted optical microscope, which is also capable of fluorescence microscopy and has a heated stage for live cell imaging.

Bruker Multimode 8

The Bruker MultiMode® 8 (MM8) is an advanced atomic force microscope (AFM) and Scanning Tunnelling Microscope (STM). Its PeakForce Tapping technology enables exceedingly low tip-sample force interactions compared to tapping mode, making it particularly useful for delicate samples by allowing the user to control the maximal force imparted to the sample. The MM8 also features the Bruker ScanAsyst® software, automating the optimisation of scanning parameters for users to obtain quality images.

Cell Sorter

The BD FACSAria™ III cell sorter is equipped with 5 excitation lasers (blue 488nm, red 642nm and violet 405nm + Yellow Green 561nm and True Blue 442nm) and can detect up to 17 parameters (15 fluorescence channels plus forward scatter and side scatter).

Cell Sorter

The BD FACSAria™ II cell sorter is equipped with three excitation lasers (blue 488nm, red 642nm and violet 405nm) and can detect up to 13 parameters (11 fluorescence channels plus forward scatter and side scatter).

Cell Sorter

The BD Influx™ cell sorter is equipped with five excitation lasers (ultraviolet 355nm, violet 405nm, blue 488nm, yellow/green 561nm and red 642nm) and has a flexible detection configuration with a number of filter set options, detecting up to 24 parameters (21 fluorescence channels, two forward scatter channels and one side scatter).

CellCelector

The ALS CellCelector is a freely configurable tool for the automated transfer of single cells and cell colonies. The patented harvest process allows a gentle cell uptake directly from the culture plate without pre-treatment. Using this technology, highest survival rate and cell integrity are guaranteed. Our new developed laminar flow cabinet allows you to work permanently under sterilizable and defined environmental conditions (temperature, CO2). A controlled cell harvest has an increasing importance for the applications of the rapidly expanding life science sector.

Chemicon Advanced Tissue Arrayer

Chemicon Advanced Tissue Arrayer ATA100 allows you to create customized arrays of multiple tissue specimens on a single histologic slide. This instrument allows to selectively remove core tissue samples from paraffin blocks and arrange those tissue samples into an array within a recipient paraffin block. The newly formed tissue array paraffin block is then ready for further histology technique processing.

Computer Processing Room

 

Ten PC's available for training and off-line processing.

 

Deformability Cytometer

The AcCellerator is a high-speed imaging cytometer for mechanical cell characterization through real-time deformability cytometry measurements.

Dynamic Light Scatter (DLS)

The Zetasizer Nano ZS is a high performance two angle particle and molecular size analyser for the enhanced detection of aggregates and measurement of small or dilute samples, and samples at very low or high concentration using dynamic light scattering with ‘NIBS’ optics. The ZSP also incorporates a zeta potential analyzer that uses electrophoretic light scattering for particles, molecules and surfaces, and a molecular weight analyzer using static light scattering.