Dr Carmel Maria Quinn

Carmel Quinn UNSW Biorepository

Project Officer

Research profile: Click to view

Biography

Dr Carmel Quinn is a Senior Project Officer working in UNSW Biospecimen Services, Mark Wainwright Analytical Centre. Carmel works predominantly with the Health Precincts Biobank (formerly the Health Science Alliance (HSA) Biobank), part of UNSW Biospecimen Services since 2021. Prior to this, Carmel worked as a Project Officer for the Translational Cancer Research Network (TCRN), where her role principally involved supporting the HSA Biobank. Carmel also worked for several years as a post-doctoral scientist in cardiovascular molecular and cell biology, first in the UK then at UNSW Sydney.

Publications

Conference Papers

Larrede S; Quinn CM; Jessup W; Frisdal E; Olivier M; Hsieh V; Couvert P; Carrie A; Giral P; Chapman M; Guerin M; Le Goff W, 2009, 'Stimulation of Cholesterol Efflux by LXR Agonists in Cholesterol-Loaded Primary Human Macrophages Is an ATP-Dependent Transport Mechanism Mediated by ABCA1 Independent of ABCG1', in Arteriosclerosis, Thrombosis and Vascular Biology, Lippincott Williams & Wilkins, United States, pp. E115 - E115, presented at 10th Annual Conference on Arteriosclerosis, Thrombosis and Vascular Biology, Washington, DC, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000267102500552&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
Out R; Lammers B; Hildebrand R; Quinn CM; Williamson D; Hoekstra M; Meurs I; Van Berkel T; Jessup W; Van Eck M, 2008, 'Deletion of Both Macrophage ABCG1 and ApoE Independently Promotes Atherosclerotic Lesion Development in LDL Receptor Knockout Mice', in Circulation, Lippincott Williams & Wilkins, Philadelphia, PA, USA, pp. S376 - S376, presented at 81st Annual Scientific Session of the American-Heart-Association, New Orleans, LA, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000262104500479&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
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Quinn CM; Kritharides L; Jessup W, 2006, 'The lipid droplet surface protein adipophilin inhibits cholesterol clearance from human macrophage foam cells', in ATHEROSCLEROSIS SUPPLEMENTS, ELSEVIER IRELAND LTD, Rome, ITALY, pp. 492 - 492, presented at 14th Meeting of the International-Society-of-Atherosclerosis, Rome, ITALY, 18 June 2006 - 22 June 2006, http://dx.doi.org/10.1016/S1567-5688(06)81964-1
Gelissen I; Harris M; Rye KA; Quinn CM; Brown AJ; Kockx M; Cartland S; Packianathan M; Kritharides L; Jessup W, 2006, 'ABCA1 and ABCG1 act sequentially to mediate cholesterol export to apoA-I', in ATHEROSCLEROSIS SUPPLEMENTS, ELSEVIER IRELAND LTD, Rome, ITALY, pp. 541 - 541, presented at 14th Meeting of the International-Society-of-Atherosclerosis, Rome, ITALY, 18 June 2006 - 22 June 2006, http://dx.doi.org/10.1016/S1567-5688(06)82178-1
Jessup W; Gaus K; Kritharides L; Boettcher A; Drobnik W; Langmann T; Schmitz G; Death A; Quinn CM; Dean RT, 2003, 'Apolipoprotein A-1 interaction with plasma membrane lipid rafts controls cholesterol export from macrophages', in ATHEROSCLEROSIS SUPPLEMENTS, ELSEVIER SCI IRELAND LTD, KYOTO, JAPAN, pp. 69 - 69, presented at 13th International Symposium on Atherosclerosis, KYOTO, JAPAN, 28 September 2003 - 02 October 2003, http://dx.doi.org/10.1016/S1567-5688(03)90298-4
Quinn CM; Brown AJ; Kritharides L; Jessup W, 2002, 'The expression and regulation of sterol 27-hydroxylase (cyp27) in human macrophages', in CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, BLACKWELL PUBLISHING ASIA, MELBOURNE, AUSTRALIA, pp. A25 - A25, presented at Joint Symposium of the Australian-Athersclerosis-Society/Australian-Vascular-Biology-Society, MELBOURNE, AUSTRALIA, 27 December 2002, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000183582000066&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Journal articles

Kang EY; Millstein J; Popovic G; Meagher NS; Bolithon A; Talhouk A; Chiu DS; Anglesio MS; Leung B; Tang K; Lambie N; Pavanello M; Da-anoy A; Lambrechts D; Loverix L; Olbrecht S; Bisinotto C; Garcia-Donas J; Ruiz-Llorente S; Yagüe-Fernandez M; Edwards RP; Elishaev E; Olawaiye A; Taylor S; Ataseven B; du Bois A; Harter P; Lester J; Høgdall CK; Armasu SM; Huang Y; Vierkant RA; Wang C; Winham SJ; Heublein S; Kommoss FKF; Cramer DW; Sasamoto N; van-Wagensveld L; Lycke M; Mateoiu C; Joseph J; Pike MC; Odunsi K; Tseng CC; Pearce CL; Bilic S; Conrads TP; Hartmann A; Hein A; Jones ME; Leung Y; Beckmann MW; Ruebner M; Schoemaker MJ; Terry KL; El-Bahrawy MA; Coulson P; Etter JL; LaVigne-Mager K; Andress J; Grube M; Fischer A; Neudeck N; Robertson G; Farrell R; Barlow E; Quinn C; Hettiaratchi A; Casablanca Y; Erber R; Stewart CJR; Tan A; Yu Y; Boros J; Brand AH; Harnett PR; Kennedy CJ; Nevins N; Morgan T; Fasching PA; Vergote I; Swerdlow AJ; Candido dos Reis FJ; Maxwell GL; Neuhausen SL; Barquin-Garcia A; Modugno F; Moysich KB; Crowe PJ; Hirasawa A; Heitz F; Karlan BY; Goode EL; Sinn P; Horlings HM; Høgdall E; Sundfeldt K; Kommoss S; Staebler A, 2022, 'MCM3 is a novel proliferation marker associated with longer survival for patients with tubo-ovarian high-grade serous carcinoma', Virchows Archiv, vol. 480, pp. 855 - 871, http://dx.doi.org/10.1007/s00428-021-03232-0
Quinn CM; Porwal M; Meagher NS; Hettiaratchi A; Power C; Jonnaggadala J; McCullough S; Macmillan S; Tang K; Liauw W; Goldstein D; Zeps N; Crowe PJ, 2021, 'Moving with the Times: The Health Science Alliance (HSA) Biobank, Pathway to Sustainability', Biomarker Insights, vol. 16, http://dx.doi.org/10.1177/11772719211005745
Kockx M; Glaros E; Leung B; Ng TW; Berbée JFP; Deswaerte V; Nawara D; Quinn C; Rye KA; Jessup W; Rensen PCN; Meikle PJ; Kritharides L, 2016, 'Low-Density Lipoprotein Receptor-Dependent and Low-Density Lipoprotein Receptor-Independent Mechanisms of Cyclosporin A-Induced Dyslipidemia', Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 36, pp. 1338 - 1349, http://dx.doi.org/10.1161/ATVBAHA.115.307030
Du XM; Kim MJ; Hou L; Le Goff W; Chapman MJ; Van Eck M; Curtiss LK; Burnett JR; Cartland SP; Quinn CM; Kockx M; Kontush A; Rye KA; Kritharides L; Jessup W, 2015, 'HDL particle size is a critical determinant of ABCA1-mediated macrophage cellular cholesterol export', Circulation Research, vol. 116, pp. 1133 - 1142, http://dx.doi.org/10.1161/CIRCRESAHA.116.305485
Traini M; Quinn CM; Sandoval C; Johansson E; Schroder K; Kockx M; Meikle PJ; Jessup W; Kritharides L, 2014, 'Sphingomyelin phosphodiesterase acid-like 3A (SMPDL3A) is a novel nucleotide phosphodiesterase regulated by cholesterol in human macrophages', Journal of Biological Chemistry, vol. 289, pp. 32895 - 32913, http://dx.doi.org/10.1074/jbc.M114.612341
Larrede S; Quinn CM; Jessup W; Frisdal E; Olivier M; Hsieh V; Kim M; Van Eck M; Couvert P; Carrie A; Giral P; Chapman J; Guerin M; Le Goff W, 2009, 'Stimulation of Cholesterol Efflux by LXR Agonists in Cholesterol-Loaded Human Macrophages Is ABCA1-Dependent but ABCG1-Independent', Arteriosclerosis, Thrombosis and Vascular Biology, vol. 29, pp. 1930 - U538, http://dx.doi.org/10.1161/ATVBAHA.109.194548
Lammers B; Out R; Hildebrand R; Quinn CM; Williamson D; Hoekstra M; Meurs I; Van Berkel T; Jessup W; Van Eck M, 2009, 'Independent protective roles for macrophage Abcg1 and Apoe in the atherosclerotic lesion development', Atherosclerosis, vol. 205, pp. 420 - 426, http://dx.doi.org/10.1016/j.atherosclerosis.2009.01.017
Wong J; Quinn CM; Gelissen I; Brown AJ, 2008, 'Endogenous 24(S),25-epoxycholesterol fine-tunes acute control of cellular cholesterol homeostasis', The Journal of Biological Chemistry, vol. 283, pp. 700 - 707, http://dx.doi.org/10.1074/jbc.M706416200
Wong J; Quinn CM; Gelissen I; Jessup W; Brown AJ, 2008, 'The effect of statins on ABCA1 and ABCG1 expression in human macrophages is influenced by cellular cholesterol levels and extent of differentiation', Atherosclerosis, vol. 196, pp. 180 - 189, http://dx.doi.org/10.1016/j.atherosclerosis.2007.03.030
Rentero C; Zech T; Quinn CM; Engelhardt K; Grewal T; Jessup W; Harder T; Gaus K; Williamson D, 2008, 'Functional implications of plasma membrane condensation for Tcell activation', PLoS One, vol. 3, pp. 1 - 6, http://dx.doi.org/10.1371/journal.pone.0002262
Glaros EN; Kim WS; Quinn CM; Jessup W; Rye K; Garner B, 2008, 'Myriocin slows the progression of established atherosclerotic lesions in apolipoprotein E gene knockout mice', Journal of Lipid Research, vol. 49, pp. 324 - 331, http://dx.doi.org/10.1194/jlr.M700261-JLR200
Glaros EN; Kim WS; Wu BJ; Suarna C; Quinn CM; Rye K; Stocker R; Jessup W; Garner B, 2007, 'Inhibition of atherosclerosis by the serine palmitoyl transferase inhibitor myriocin is associated with reduced plasma glycosphingolipid concentration', Biochemical Pharmacology, vol. 73, pp. 1340 - 1346, http://dx.doi.org/10.1016/j.bcp.2006.12.023
Wong J; Quinn CM; Brown AJ, 2007, 'Synthesis of the oxysterol, 24(S), 25-epoxycholesterol, parallels cholesterol production and may protect against cellular accumulation of newly-synthesized cholesterol', Lipids in Health and Disease, vol. 6, http://dx.doi.org/10.1186/1476-511X-6-10
Wong J; Quinn CM; Guillemin GJ; Brown AJ, 2007, 'Primary human astrocytes product 24(S),25-epoxycholesterol with implications for brain cholesterol homeostasis', Journal of Neurochemistry, vol. 103, pp. 1764 - 1773, http://dx.doi.org/10.1111/j.1471-4159.2007.04913.x
Jessup W; Gelissen I; Kritharides L; Quinn CM; Kockx M; Brown AJ; Rye K; Harris M; Packianathan M; Cartland SP, 2006, 'ABCA1 and ABCG1 Synergize to Mediate Cholesterol Export to ApoA-I', Arteriosclerosis, Thrombosis and Vascular Biology, vol. 26, pp. 534 - 540, http://dx.doi.org/10.1161/01.ATV.0000200082.58536.e1
Wong J; Quinn CM; Brown AJ, 2006, 'SREBP-2 positively regulates transcription of the cholesterol efflux gene, ABCA1, by generating oxysterol ligands for LXR', Biochemical Journal, vol. 400, pp. 485 - 491, http://dx.doi.org/10.1042/BJ20060914
Gelissen I; Rye K-A; Quinn C; Brown A; Kockx M; Cartland S; Kritharides L; Jessup W, 2006, 'Concerted action of ABCA1 and ABCG1 in cell cholesterol export', Vascular Pharmacology, vol. 45, pp. e23 - e23, http://dx.doi.org/10.1016/j.vph.2006.08.107
Glaros EN; Kim WS; Quinn CM; Wong J; Gelissen I; Jessup W; Garner B, 2005, 'Glycosphingolipid accumulation inhibits cholesterol efflux via the ABCA1/apolipoprotein A-I pathway 1-Phenyl-2-decanoylamino-3-morpholino-1-propanol is a novel cholesterol efflux accelerator', The Journal of Biological Chemistry, vol. 280, pp. 24515 - 24523, http://dx.doi.org/10.1074/jbc.M413862200
Quinn CM; Jessup W; Wong J; Kritharides L; Brown AJ, 2005, 'Expression and regulation of sterol 27-hydroxylase (CYP27A1) in humanmacrophages: a role for RXR and PPAR gamma ligands', Biochemical Journal, vol. 385, pp. 823 - 830, http://dx.doi.org/10.1042/BJ20041776
Gelissen I; Packianathan M; Rye K; Harris ML; Quinn CM; Kritharides L; Jessup W, 2005, 'ABCG1 mediated cholesterol efflux from cells', Atherosclerosis Supplements, vol. 6, pp. 55 - 55, http://dx.doi.org/10.1016/S1567-5688(05)80220-X
Brown AJ; Wong J; Quinn CM, 2005, 'Human macrophages can synthesise de novo an oxysterol ligand for the liver X receptor: Effects of statins and consequences for cholesterol efflux', Atherosclerosis Supplements, vol. 6, pp. 96 - 96, http://dx.doi.org/10.1016/S1567-5688(05)80379-4
Kockx M; Rye K; Gaus K; Quinn CM; Wright J; Sloane T; Sviridov D; Fu YL; Sullivan D; Burnett J; Rust S; Assmann G; Anantharamaiah G; Palgunachari M; Katz S; Phillips MA; Dean R; Jessup W; Kritharides L, 2004, 'Apolipoprotein A-I-stimulated apolipoprotein E secretion from human macrophages is independent of cholesterol efflux', The Journal of Biological Chemistry, vol. 279, pp. 25966 - 25977, http://dx.doi.org/10.1074/jbc.M401177200
Gaus K; Kritharides L; Schmitz G; Boettcher A; Drobnik W; Langmann T; Quinn CM; Death A; Dean R; Jessup W, 2004, 'Apolipoprotein A-1 interaction with plasma membrane lipid rafts controls cholesterol export from macrophages', The FASEB Journal, vol. 18, pp. 574 - 576
Wong J; Quinn CM; Brown AJ, 2004, 'Statins inhibit synthesis of an oxysterol ligand for the liver x receptor in human macrophages with consequences for cholesterol flux', Arteriosclerosis, Thrombosis and Vascular Biology, vol. 24, pp. 2365 - 2371, http://dx.doi.org/10.1161/01.ATV.0000148707.93054.7d
Quinn CM; Kagedal K; Terman A; Stroikin U; Brunk U; Jessup W; Garner B, 2004, 'Induction of fibroblast apolipoprotein E expression during apoptosis, starvation-induced growth arrest and mitosis', Biochemical Journal, vol. 378, pp. 753 - 761
O Reilly D; Addley M; MacFarlane AJ; Gordon S; McKnight AJ; Greaves DR; Quinn CM, 2004, 'Functional analysis of the murine Emr1 promoter identifies a novel purine-rich regulatory motif required for high-level gene expression in macrophages', Genomics, vol. 84, pp. 1130 - 1140
Ng MKC; Quinn CM; McCrohon JA; Nakhla S; Jessup W; Handelsman DJ; Celermajer DS; Death AK, 2003, 'Androgens up-regulate atherosclerosis-related genes in macrophages from males but not females: Molecular insights into gender differences in atherosclerosis', Journal of the American College of Cardiology, vol. 42, pp. 1306 - 1313, http://dx.doi.org/10.1016/j.jacc.2003.07.002
Jessup W; Quinn CM; Brown AJ; Kritharides L, 2003, 'Expression and regulation of sterol 27-hydroxylase (CYP27A1) in humanmacrophages', Atherosclerosis Supplements, vol. 4, pp. 219 - 219, http://dx.doi.org/10.1016/S1567-5688(03)90935-4
Quinn CM; Kagedal K; Terman A; Stroikin U; Brunk U; Jessup W; Garner B, 2003, 'Induction of fibroblast apolipoprotein-E expression during apoptosis, starvation-induced growth arrest and mitosis', Biochemical Journal, vol. On-line, pp. 753 - 761, http://dx.doi.org/10.1042/BJ20031352
Ng M; Quinn CM; McCrohon J; Nakhla S; Jessup W; Handelsman D; Celermajer D; Death A, 2003, 'Androgens Up-Regulate Atherosclerosis-Related Genes in Macrophages Froms Males But Not Females', Journal of the American College of Cardiology, vol. 42, pp. 1306 - 1313
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Location

Level 4
Lowy Cancer Research Centre (C25)

Contact

02 9385 0564