Project Officer
Facility:
Category: General/Technical Staff
Research profile: Click to view
Biography
Dr Carmel Quinn is a Senior Project Officer working in UNSW Biospecimen Services, Mark Wainwright Analytical Centre. Carmel works predominantly with the Health Precincts Biobank (formerly the Health Science Alliance (HSA) Biobank), part of UNSW Biospecimen Services since 2021. Prior to this, Carmel worked as a Project Officer for the Translational Cancer Research Network (TCRN), where her role principally involved supporting the HSA Biobank. Carmel also worked for several years as a post-doctoral scientist in cardiovascular molecular and cell biology, first in the UK then at UNSW Sydney.
Publications
Conference Papers
, 2009, 'Stimulation of Cholesterol Efflux by LXR Agonists in Cholesterol-Loaded Primary Human Macrophages Is an ATP-Dependent Transport Mechanism Mediated by ABCA1 Independent of ABCG1', in Arteriosclerosis, Thrombosis and Vascular Biology, Lippincott Williams & Wilkins, United States, pp. E115 - E115, presented at 10th Annual Conference on Arteriosclerosis, Thrombosis and Vascular Biology, Washington, DC, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000267102500552&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
, 2008, 'Deletion of Both Macrophage ABCG1 and ApoE Independently Promotes Atherosclerotic Lesion Development in LDL Receptor Knockout Mice', in Circulation, Lippincott Williams & Wilkins, Philadelphia, PA, USA, pp. S376 - S376, presented at 81st Annual Scientific Session of the American-Heart-Association, New Orleans, LA, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000262104500479&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
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, 2006, 'ABCA1 and ABCG1 act sequentially to mediate cholesterol export to apoA-I', in ATHEROSCLEROSIS SUPPLEMENTS, ELSEVIER IRELAND LTD, ITALY, Rome, pp. 541 - 541, presented at 14th Meeting of the International-Society-of-Atherosclerosis, ITALY, Rome, 18 June 2006 - 22 June 2006, http://dx.doi.org/10.1016/S1567-5688(06)82178-1
, 2006, 'The lipid droplet surface protein adipophilin inhibits cholesterol clearance from human macrophage foam cells', in ATHEROSCLEROSIS SUPPLEMENTS, ELSEVIER IRELAND LTD, ITALY, Rome, pp. 492 - 492, presented at 14th Meeting of the International-Society-of-Atherosclerosis, ITALY, Rome, 18 June 2006 - 22 June 2006, http://dx.doi.org/10.1016/S1567-5688(06)81964-1
, 2003, 'Apolipoprotein A-1 interaction with plasma membrane lipid rafts controls cholesterol export from macrophages', in ATHEROSCLEROSIS SUPPLEMENTS, ELSEVIER SCI IRELAND LTD, JAPAN, KYOTO, pp. 69 - 69, presented at 13th International Symposium on Atherosclerosis, JAPAN, KYOTO, 28 September 2003 - 02 October 2003, http://dx.doi.org/10.1016/S1567-5688(03)90298-4
, 2002, 'The expression and regulation of sterol 27-hydroxylase (cyp27) in human macrophages', in CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, BLACKWELL PUBLISHING ASIA, AUSTRALIA, MELBOURNE, pp. A25 - A25, presented at Joint Symposium of the Australian-Athersclerosis-Society/Australian-Vascular-Biology-Society, AUSTRALIA, MELBOURNE, 27 December 2002, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000183582000066&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Journal articles
, 2023, 'CCNE1 and survival of patients with tubo-ovarian high-grade serous carcinoma: An Ovarian Tumor Tissue Analysis consortium study', Cancer, 129, pp. 697 - 713, http://dx.doi.org/10.1002/cncr.34582
, 2022, 'MCM3 is a novel proliferation marker associated with longer survival for patients with tubo-ovarian high-grade serous carcinoma', Virchows Archiv, 480, pp. 855 - 871, http://dx.doi.org/10.1007/s00428-021-03232-0
, 2022, 'Gene-Expression Profiling of Mucinous Ovarian Tumors and Comparison with Upper and Lower Gastrointestinal Tumors Identifies Markers Associated with Adverse Outcomes', Clinical Cancer Research, 28, pp. 5383 - 5395, http://dx.doi.org/10.1158/1078-0432.CCR-22-1206
, 2021, 'Moving with the Times: The Health Science Alliance (HSA) Biobank, Pathway to Sustainability', Biomarker Insights, 16, pp. 1 - 10, http://dx.doi.org/10.1177/11772719211005745
, 2016, 'Low-Density Lipoprotein Receptor-Dependent and Low-Density Lipoprotein Receptor-Independent Mechanisms of Cyclosporin A-Induced Dyslipidemia', Arteriosclerosis, Thrombosis, and Vascular Biology, 36, pp. 1338 - 1349, http://dx.doi.org/10.1161/ATVBAHA.115.307030
, 2015, 'HDL particle size is a critical determinant of ABCA1-mediated macrophage cellular cholesterol export', Circulation Research, 116, pp. 1133 - 1142, http://dx.doi.org/10.1161/CIRCRESAHA.116.305485
, 2014, 'Sphingomyelin phosphodiesterase acid-like 3A (SMPDL3A) is a novel nucleotide phosphodiesterase regulated by cholesterol in human macrophages', Journal of Biological Chemistry, 289, pp. 32895 - 32913, http://dx.doi.org/10.1074/jbc.M114.612341
, 2014, 'Abstract 230: Stimulation of Cholesterol Efflux from Human Macrophage by Liver X Receptor Agonists is a 2-Step Mechanism Requiring ARL7 and ABCA1', Arteriosclerosis, Thrombosis, and Vascular Biology, 34, http://dx.doi.org/10.1161/atvb.34.suppl_1.230
, 2014, 'ABCG1 is involved in vitamin E efflux.', Biochim Biophys Acta, 1841, pp. 1741 - 1751, http://dx.doi.org/10.1016/j.bbalip.2014.10.003
, 2009, 'Independent protective roles for macrophage Abcg1 and Apoe in the atherosclerotic lesion development', Atherosclerosis, 205, pp. 420 - 426
, 2009, 'Stimulation of Cholesterol Efflux by LXR Agonists in Cholesterol-Loaded Human Macrophages Is ABCA1-Dependent but ABCG1-Independent', Arteriosclerosis, Thrombosis and Vascular Biology, 29, pp. 1930 - U538
, 2009, 'Abstract: 622 INDEPENDENT PROTECTIVE ROLES FOR MACROPHAGE ABCG1 AND APOE IN ATHEROSCLEROTIC LESION DEVELOPMENT', Atherosclerosis Supplements, 10, pp. e370 - e370, http://dx.doi.org/10.1016/s1567-5688(09)70364-2
, 2009, 'Abstract: P732 HYPERLIPIDEMIC SERUM ALTERS MACROPHAGE LIPID CONTENT, FATTY ACID COMPOSITION AND GENE EXPRESSION', Atherosclerosis Supplements, 10, pp. e918 - e918, http://dx.doi.org/10.1016/s1567-5688(09)70900-6
, 2009, 'Abstract: S3-24 INDEPENDENT PROTECTIVE ROLES FOR MACROPHAGE ABCG1 AND APOE IN ATHEROSCLEROTIC LESION DEVELOPMENT', Atherosclerosis Supplements, 10, pp. e1536 - e1536, http://dx.doi.org/10.1016/s1567-5688(09)71489-8
, 2008, 'Functional implications of plasma membrane condensation for Tcell activation', PLoS One, 3, pp. 1 - 6
, 2008, 'The effect of statins on ABCA1 and ABCG1 expression in human macrophages is influenced by cellular cholesterol levels and extent of differentiation', Atherosclerosis, 196, pp. 180 - 189, http://dx.doi.org/10.1016/j.atherosclerosis.2007.03.030
, 2008, 'Endogenous 24(S),25-epoxycholesterol fine-tunes acute control of cellular cholesterol homeostasis', The Journal of Biological Chemistry, 283, pp. 700 - 707, http://dx.doi.org/10.1074/jbc.M706416200
, 2008, 'Myriocin slows the progression of established atherosclerotic lesions in apolipoprotein E gene knockout mice', Journal of Lipid Research, 49, pp. 324 - 331, http://dx.doi.org/10.1194/jlr.M700261-JLR200
, 2008, 'Abstract 1721: Deletion of Both Macrophage ABCG1 and ApoE Independently Promotes Atherosclerotic Lesion Development in LDL Receptor Knockout Mice', Circulation, 118, http://dx.doi.org/10.1161/circ.118.suppl_18.s_376-b
, 2007, 'Synthesis of the oxysterol, 24(S), 25-epoxycholesterol, parallels cholesterol production and may protect against cellular accumulation of newly-synthesized cholesterol', Lipids in Health and Disease, 6
, 2007, 'Primary human astrocytes product 24(S),25-epoxycholesterol with implications for brain cholesterol homeostasis', Journal of Neurochemistry, 103, pp. 1764 - 1773
, 2007, 'Inhibition of atherosclerosis by the serine palmitoyl transferase inhibitor myriocin is associated with reduced plasma glycosphingolipid concentration', Biochemical Pharmacology, 73, pp. 1340 - 1346
, 2006, 'ABCA1 and ABCG1 Synergize to Mediate Cholesterol Export to ApoA-I', Arteriosclerosis, Thrombosis and Vascular Biology, 26, pp. 534 - 540
, 2006, 'SREBP-2 positively regulates transcription of the cholesterol efflux gene, ABCA1, by generating oxysterol ligands for LXR', Biochemical Journal, 400, pp. 485 - 491
, 2006, 'Concerted action of ABCA1 and ABCG1 in cell cholesterol export', Vascular Pharmacology, 45, pp. e23 - e23, http://dx.doi.org/10.1016/j.vph.2006.08.107
, 2005, 'Glycosphingolipid accumulation inhibits cholesterol efflux via the ABCA1/apolipoprotein A-I pathway 1-Phenyl-2-decanoylamino-3-morpholino-1-propanol is a novel cholesterol efflux accelerator', The Journal of Biological Chemistry, 280, pp. 24515 - 24523
, 2005, 'Expression and regulation of sterol 27-hydroxylase (CYP27A1) in humanmacrophages: a role for RXR and PPAR gamma ligands', Biochemical Journal, 385, pp. 823 - 830
, 2005, 'Human macrophages can synthesise de novo an oxysterol ligand for the liver X receptor: Effects of statins and consequences for cholesterol efflux', Atherosclerosis Supplements, 6, pp. 96 - 96
, 2005, 'ABCG1 mediated cholesterol efflux from cells', Atherosclerosis Supplements, 6, pp. 55 - 55
, 2004, 'Statins inhibit synthesis of an oxysterol ligand for the liver x receptor in human macrophages with consequences for cholesterol flux', Arteriosclerosis, Thrombosis and Vascular Biology, 24, pp. 2365 - 2371, http://www.sciencedirect.com/science/article/B6WVB-4DYM7R6-1F1/2/3c81550ef6b4b3f41c3b52d70fee5c03
, 2004, 'Apolipoprotein A-I-stimulated apolipoprotein E secretion from human macrophages is independent of cholesterol efflux', The Journal of Biological Chemistry, 279, pp. 25966 - 25977
, 2004, 'Apolipoprotein A-1 interaction with plasma membrane lipid rafts controls cholesterol export from macrophages', The FASEB Journal, 18, pp. 574 - 576
, 2004, 'Induction of fibroblast apolipoprotein E expression during apoptosis, starvation-induced growth arrest and mitosis', Biochemical Journal, 378, pp. 753 - 761
, 2004, 'Functional analysis of the murine Emr1 promoter identifies a novel purine-rich regulatory motif required for high-level gene expression in macrophages', Genomics, 84, pp. 1130 - 1140
, 2003, 'Androgens up-regulate atherosclerosis-related genes in macrophages from males but not females: Molecular insights into gender differences in atherosclerosis', Journal of the American College of Cardiology, 42, pp. 1306 - 1313, http://dx.doi.org/10.1016/j.jacc.2003.07.002
, 2003, 'Induction of fibroblast apolipoprotein-E expression during apoptosis, starvation-induced growth arrest and mitosis', Biochemical Journal, On-line
, 2003, 'Expression and regulation of sterol 27-hydroxylase (CYP27A1) in humanmacrophages', Atherosclerosis Supplements, 4, pp. 219 - 219
, 2003, 'Gender differences in macrophange gene regulation — molecular insights into androgens and atherogenesis', Heart, Lung and Circulation, 12, pp. A25 - A25, http://dx.doi.org/10.1046/j.1443-9506.2003.01260.x
, 2003, 'Androgens Up-Regulate Atherosclerosis-Related Genes in Macrophages Froms Males But Not Females', Journal of the American College of Cardiology, 42, pp. 1306 - 1313
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Location
Level 4
Lowy Cancer Research Centre (C25)
Lowy Cancer Research Centre (C25)
