Instruments

The Molecular Surface Interaction Lab is in Building E26, Level 2, Room 2002 within BMSF. Please contact msi@unsw.edu.au for instrument enquiry.

BiaCore T200 (Surface Plasmon Resonance, SPR)

BiaCore T200​​

BiaCore T200 uses an optical technique, surface plasmon resonance (SPR), to measure label-free detection of small molecule/protein/peptide/antibody interactions. The system has four channels and is capable of auto-sampling and allowing multiplexing of experiments for high throughput. This instrument provides:

  • Kinetic and affinity analyses
  • Biomolecular interactions
  • Calibration-free concentration analysis
  • Screening processes
  • Epitope mapping

QSense Analyzer (Quartz Crystal Microbalance with Dissipation monitoring, QCMD)

 QCMD

QSense Analyzer (Quartz crystal microbalance with dissipation monitoring) uses acoustic and gravimetric techniques that allow label-free, real-time measurement of interactions between surface immobilised materials, molecules or cells with ng/cm2 resolution. The QSense Analyzer system has four channels allowing multiplexing of experiments for high throughput. This device provides:

  • Viscoelastic measurements
  • Thickness, structure and layer properties measurements
  • Kinetics and affinity analyses
  • capability to be equipped with an electrochemical module allowing simultaneous electrochemical impedance spectroscopy measurements or a cell module enabling simultaneous microscopy imaging.

BLItz (Bio-layer interferometry)

BLItz

BLItz interferometry-based biosensor enables label-free real-time analysis of protein interactions in a minimum sample volume of 4 μL. This is a single channel, manually operated instrument and ideally suited to simple and low volume experiments. This instrument is particularly suited for:

  • Determination of a particular protein in a crude or purified sample
  • Kinetic and affinity analyses
  • Protein/antibody quantitation
  • Rapid immunoassay development