Ms Sonia Bustamante


Analytical Chemist



BChem(Hons)(Analytical Chemistry), San Marcos National University, Peru
MChem(Food and Drug Analysis), UNSW Australia

Role & Interests

My work involves the characterisation and/or quantitation of small molecule metabolites in biological systems by GC-MS and LC-MS. Current projects/assays include: Isotope dilution GCMS; Analysis of catecholamines & Kynurenine Pathway metabolites; Nitrates and Nitrites; Glucose; Hormones; Acetylecholine and other quaternary ammonium biological amines; Vitamin D and metabolites. My interest is in targeted metabolomics and the development of quantitative methods. Other duties include training students and other users in the laboratory as well as instrumental techniques.


Book Chapters

Jayasena T; Bustamante S; Clement J; Welschinger R; Caplan GA; Sachdev PS; Braidy N, 2020, 'Clinical Assessment of the NADome as Biomarkers for Healthy Aging', in Guest PC (ed.), Clinical and Preclinical Models for Maximizing Healthspan Methods and Protocols, Humana, pp. 207 - 216,

Conference Abstracts

Poljak A; Matayatsuk C; Bustamante S; Sachdev PS; Brodaty H, 2006, 'Quantification of O- and M-tyrosine levels in Alzheimer’s plasma proteins [Abstract Poster PO077]', in Neuropsychiatric Disease and Treatment, Dove Medical Press, Cheshire, UK, Vol. 2, pp. S148 - S148, presented at 6th International Neuropsychiatric Association Congress, Sydney, 10 September 2006 - 14 September 2006
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Conference Papers

Adams S; Teo C; McDonald KL; Zinger A; Bustamante S; Lim CK; Sundaram G; Braidy N; Brew BJ; Guillemin GJ, 2014, 'Involvement of the kynurenine pathway in human glioma pathophysiology', in PLoS ONE,

Journal articles

Bertoldo MJ; Listijono DR; Ho WHJ; Riepsamen AH; Goss DM; Richani D; Jin XL; Mahbub S; Campbell JM; Habibalahi A; Loh WGN; Youngson NA; Maniam J; Wong ASA; Selesniemi K; Bustamante S; Li C; Zhao Y; Marinova MB; Kim LJ; Lau L; Wu RM; Mikolaizak AS; Araki T; Le Couteur DG; Turner N; Morris MJ; Walters KA; Goldys E; O'Neill C; Gilchrist RB; Sinclair DA; Homer HA; Wu LE, 2020, 'NAD+ Repletion Rescues Female Fertility during Reproductive Aging', Cell Reports, vol. 30, pp. 1670 - 1681.e7,
Yadav S; Dudchenko O; Esvaran M; Rosen B; Field M; Skvortsova K; Gopalakrishnan S; Keilwagen J; Cockran B; Manandhar B; Bucknall M; Bustamante S; Rasmussen J; Melvin R; Omer A; Colaric, Z; Chan E; Minoche A; Smith T; Gilbert T; Bogdanovic O; Zammit R; Thomas T; Aiden E; Ballard B, 2020, 'Desert Dingo (Canis lupus dingo) genome provides insights into their role in the Australian ecosystem', bioRix,
Heng B; Bilgin AA; Lovejoy DB; Tan VX; Milioli HH; Gluch L; Bustamante S; Sabaretnam T; Moscato P; Lim CK; Guillemin GJ, 2020, 'Differential kynurenine pathway metabolism in highly metastatic aggressive breast cancer subtypes: beyond IDO1-induced immunosuppression', Breast Cancer Research, vol. 22,
Wasinger VC; Curnoe D; Bustamante S; Mendoza R; Shoocongdej R; Adler L; Baker A; Chintakanon K; Boel C; Tacon PSC, 2019, 'Analysis of the Preserved Amino Acid Bias in Peptide Profiles of Iron Age Teeth from a Tropical Environment Enable Sexing of Individuals Using Amelogenin MRM', Proteomics, vol. 19, pp. e1800341,
Richani D; Lavea CF; Kanakkaparambil R; Riepsamen AH; Bertoldo MJ; Bustamante S; Gilchrist RB, 2019, 'Participation of the adenosine salvage pathway and cyclic AMP modulation in oocyte energy metabolism', Scientific Reports, vol. 9, pp. 18395,
Bajracharya R; Bustamante S; Ballard JWO, 2019, 'Stearic acid supplementation in high protein to carbohydrate (P:C) Ratio diet improves physiological and mitochondrial functions of Drosophila melanogaster parkin null mutants', Journals of Gerontology - Series A Biological Sciences and Medical Sciences, vol. 74, pp. 1564 - 1572,
Bustamante S; Jayasena T; Richani D; Gilchrist RB; Wu LE; Sinclair DA; Sachdev PS; Braidy N, 2018, 'Quantifying the cellular NAD+ metabolome using a tandem liquid chromatography mass spectrometry approach', Metabolomics, vol. 14,
Aw WC; Towarnicki SG; Melvin RG; Youngson NA; Garvin MR; Hu Y; Nielsen S; Thomas T; Pickford R; Bustamante S; Vila-Sanjurjo A; Smyth GK; Ballard JWO, 2018, 'Genotype to phenotype: Diet-by-mitochondrial DNA haplotype interactions drive metabolic flexibility and organismal fitness', PLoS Genetics, vol. 14, pp. e1007735,
Chowdhury MKH; Turner N; Bentley NL; Das A; Wu LE; Richani D; Bustamante S; Gilchrist RB; Morris MJ; Shepherd PR; Smith GC, 2017, 'Niclosamide reduces glucagon sensitivity via hepatic PKA inhibition in obese mice: Implications for glucose metabolism improvements in type 2 diabetes', Scientific Reports, vol. 7,
Papa I; Saliba D; Ponzoni M; Bustamante S; Canete PF; Gonzalez-Figueroa P; McNamara HA; Valvo S; Grimbaldeston M; Sweet RA; Vohra H; Cockburn IA; Meyer-Hermann M; Dustin ML; Doglioni C; Vinuesa CG, 2017, 'TFH-derived dopamine accelerates productive synapses in germinal centres', Nature, vol. 547, pp. 318 - 323,
Lim CK; Bilgin A; Lovejoy DB; Tan V; Bustamante S; Taylor BV; Bessede A; Brew BJ; Guillemin GJ, 2017, 'Kynurenine pathway metabolomics predicts and provides mechanistic insight into multiple sclerosis progression', Scientific Reports, vol. 7,
Bustamante S; Gilchrist RB; Richani D, 2017, 'A sensitive method for the separation and quantification of low-level adenine nucleotides using porous graphitic carbon-based liquid chromatography and tandem mass spectrometry', Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, vol. 1061-1062, pp. 445 - 451,
Gahreman DE; Boutcher YN; Bustamante S; Boutcher SH, 2016, 'The combined effect of green tea and acute interval sprinting exercise on fat oxidation of trained and untrained males', Journal of Exercise Nutrition & Biochemistry, vol. 20, pp. 1 - 8,
Sheipouri D; Grant R; Bustamante S; Lovejoy D; Guillemin GJ; Braidy N, 2015, 'Characterisation of the kynurenine pathway in skin-derived fibroblasts and keratinocytes', Journal of Cellular Biochemistry, vol. 116, pp. 903 - 922,
Adams S; Teo C; McDonald KL; Zinger A; Bustamante S; Lim CK; Sundaram G; Braidy N; Brew BJ; Guillemin GJ, 2014, 'Involvement of the Kynurenine Pathway in Human Glioma Pathophysiology', PLOS ONE, vol. 9,
Yau YY; Leong RWL; Shin S; Bustamante S; Pickford R; Hejazi L; Campbell B; Wasinger VC, 2014, 'Bimodal plasma metabolomics strategy identifies novel inflammatory metabolites in inflammatory bowel diseases', Discovery Medicine, vol. 18, pp. 113 - 124
Purves-Tyson TD; Handelsman D; Double KL; Bustamante S; owens SJ; Shannon Weickert C, 2012, 'Testosterone regulation of sex steroid-related mRNAs and dopamine-related mRNAs in adolescent male rat substantia nigra', BMC Neuroscience, vol. 13, pp. 95,
Phillips PA; Yang L; Shulkes A; Vonlaufen A; Poljak A; Bustamante S; Warren A; Xu ; Guilhaus M; Pirola R; Apte MV; Wilson JS, 2010, 'Pancreatic stellate cells produce acetylcholine and may play a role in pancreatic exocrine secretion', Proceedings of the National Academy of Sciences of the United States of America, vol. 107, pp. 17397 - 17402,
Bustamante S; Pickford R; Shin S; Luber R; Campbell B; Redmond D; Yau Y; Leong RWL; Wasinger V, 2010, 'Metabolomics in inflammatory bowel disease', JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, vol. 25, pp. A83 - A83,
Phillips PA; Yang L; Poljak A; Bustamante S; Shulkes A; Vonlaufen A; Xu Z; Guilhaus M; Pirola R; Apte M; Wilson J, 2009, 'Pancreatic Stellate Cells Stimulate Acinar Enzyme Secretion Via the Production of Acetylcholine', PANCREAS, vol. 38, pp. 1038 - 1039,
Phillips PA; Yang L; Poljak A; Bustamante S; Shulkes A; Vonlaufen A; Xu Z; Pirola R; Apte M; Wilson J, 2009, 'Pancreatic stellate cells synthesise and secrete acetylcholine: a potential role in enzyme secretion', JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, vol. 24, pp. A335 - A335,
Matayatsuk C; Poljak A; Bustamante S; Smythe GA; Kalpravidh R; Sirankapracha P; Fucharoen S; Wilairat P, 2007, 'Quantitative determination of ortho- and meta-tyrosine as biomarkers of protein oxidative damage in beta-thalassemia', Redox Report, vol. 12, pp. 219 - 228,
Clark CJ; Mackay G; Smythe GA; Stone T; Phillips R; Bustamante S, 2005, 'Prolonged survival of a murine model of cerebral malaria by kynurenine pathway inhibition', Infection and Immunity, vol. 73, pp. 5249 - 5251,
Smythe G; Poljak A; Bustamante S; Braga O; Maxwell A; Grant R; Perminder S, 2003, 'GC-MS analysis of picolinic and quinolinic acids and their amides in human plasma, CSF, and brain tissue', Developments in Tryptophan and Serotonin Metabolism, vol. 527, pp. 705 - 712
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