Calorimetry

Calorimetry is the study of measuring heat changes from chemical reactions or physical changes.

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GE Healthcare iTC200 Isothermal Calorimeter

Investigating molecular interactions, reaction kinetics and thermodynamics by Isothermal Calorimeter (iTC). Production or absorption of heat is a universal event consequent to the binding of two molecules or a chemical reaction. iTC is the only equipment that can directly measure the energetics of biochemical processes involving interaction between two molecules such as a receptor and a ligand.

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TA Instruments NanoDSC

This capillary Differential Scanning Calorimeter can be used for investigating the stability of proteins, nucleic acids, lipids and other macromolecules. Differential Scanning Calorimetry (DSC) is the only method that directly measures the stability of macromolecules in solution. The information obtained provides valuable insights into the factors (e.g. hydrophobic interactions, hydrogen bonding, conformational entropy and physical environment) that stabilize these biomolecules alone or as complexes, such as protein-ligand or micellar complexes.

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