Dr Carl Andrew Power

Head of Biological Resources Imaging Laboratory

Category: Academic Staff
Research profile: Click to view

Biography

Dr Carl Power is the Head of the Biological Resources Imaging Laboratory in the Mark Wainwright Analytical Centre 

Research Interests:

As head of BRIL, Dr Power has diverse interests in Preclinical imaging techniques including MRI, PET, CT, Optical Imaging and Ultrasound.
In the area of cancer biology in general and specifically prostate cancer biology, research is focused on use of animal models to identify mechanisms of prostate cancer metastasis to bone, immune responses to prostate cancer and its bone metastases and preclinical assessment of treatments to prevent bone mets.

Broad Research Areas:
Preclinical Imaging, Cancer, Immunology, Cell Biology and Gene Regulation

Qualifications:
PhD, MSc, BSc

Society Memberships & Professional Activities: Member of the World Molecular Imaging Society

 

Specific Research Keywords:
Preclinical Imaging, Prostate Cancer, Bone Metastasis, Cancer Progression, Immunology,

Publications

Book Chapters

Xiao W; Graham PH; Power C; Li Y, 2010, 'Biomarkers for radiosensitivity and radiosensitivity targets in prostate cancer', in Nguyen SD (ed.), Tumour Suppressors, Nova Science Publishers, USA, pp. 189 - 228

Conference Papers

Mattner F; Hung T-T; Bourdier T; Lee B; Henderson D; Poon J; Doan J; Power C; Katsifis A; Fulham M, 2015, 'Evaluation of F-18-TSPO radiotracers in a prostate tumour model using PET', in JOURNAL OF NUCLEAR MEDICINE, SOC NUCLEAR MEDICINE INC, Baltimore, MD, presented at Annual Meeting of the Society-of-Nuclear-Medicine-and-Molecular-Imaging, Baltimore, MD, 06 June 2015 - 10 June 2015, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000358738801206&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
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Reilhac A; Nezich R; Price R; Besmer A; Sunn N; Power C; Zahra D; Hamze H; Boisson F; Gregoire M-C, 2014, 'IMAGE-QUALITY ASSESSMENT OF SEVERAL POSITRON EMITTERS FOR PRECLINICAL IMAGING', in INTERNAL MEDICINE JOURNAL, WILEY-BLACKWELL, pp. 33 - 33, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000334282000098&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
Hung TT; Russell PJ; Power C, 2010, 'Circulating and tumour-infiltrating CD4+IL-17+ T-cells in mice bearing orthotopic and heterotopic prostate tumours', in Proceedings of the American Association for Cancer Research, American Association Cancer Research, Philadelphia, PA, USA, pp. 1162 - 1162, presented at AACR 101st Annual Meeting, Walter E.Washington Convention Centre, Washington DC, 17 April 2010 - 21 April 2010
Power C; Cho J; Pwint H; Hung TT; Russell PJ, 2009, 'Combined Docetaxel and Zoledronic Acid Treatment for Bone Metastatic Murine Prostate Cancer.', in Cancer & Bone Society, VIIIth International Meeting on Cancer Induced Bone Disease, Online, presented at VIIIth International Meeting on Cancer Induced Bone Disease, Sydney, 25 March 2009 - 26 March 2009
Li Y; Wang JQ; Rizvi SM; Cozzi PJ; Madigan MC; Power C; Russell PJ; Allen BJ, 2006, 'Control of DU 145 and LNCaP-LN3 prostate cancer spheroid growth using 213Bi-labeled multiple targeted alpha radioimmunoconjugates', in Annals of Oncology, Oxford Univ Press, Oxford, England, pp. 47 - 47, presented at Symposium on targeted anticancer therapies, Amsterdam, 16 March 2006 - 18 March 2006, http://dx.doi.org/10.1093/annonc/mdl921
Tse B; Russell PJ; Power C, 2005, 'IL-18 expression inhibits growth of RM1 murine prostate carcinomas', in Tissue Antigens, Blackwell Munksgaard, Copenhagen, Denmark, pp. 568 - 568, presented at Genetics and The Immune Response’ Abstracts of the 35th Annual Scientific Meeting of the Australasian Society for Immunology and 14th International HLA & Immunogenetics Workshop, Melbourne, AUSTRALIA, 29 November 2005 - 02 December 2005, http://dx.doi.org/10.1111/j.1399-0039.2005.00523.x
Hung TT; Power C; Russell PJ, 2005, 'Inhibition of tumorigenicity of invasive human bladder cancer cells by a non-tumorigenic subline from the same xenograft: Identification of differentially expressed genes.', in Cancer epidemiology biomarkers and prevention, American Association Cancer Research, Philadelphia, PA, USA, pp. 2742S - 2743S, presented at 4th Annual Conference on Frontiers in Cancer Prevention Research, Washington, 30 October 2005 - 02 November 2005, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000233351200253&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
Fazekas de St Groth B; Seddiki N; Tan S; Higgins C; Power C; Santner-Nanan B; Nanan R; Sasson S; Zaunders J; Kelleher A; Landay A, 2005, 'Regulatory T cells and the maintenance of tolerance', in TISSUE ANTIGENS, BLACKWELL PUBLISHING, Melbourne, AUSTRALIA, pp. 412 - 412, presented at 35th Annual SCientific Meeting of the Australasian-Society-for-Immunology/14th International HLA and Immunogenetics Workshops, Melbourne, AUSTRALIA, 29 November 2005 - 02 December 2005, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000233542700194&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a

Journal articles

Rashid I; Maghzal GJ; Chen YC; Cheng D; Talib J; Newington D; Ren M; Vajandar SK; Searle A; Maluenda A; Lindstedt EL; Jabbour A; Kettle AJ; Bongers A; Power C; Michaëlsson E; Peter K; Stocker R, 2018, 'Myeloperoxidase is a potential molecular imaging and therapeutic target for the identification and stabilization of high-risk atherosclerotic plaque', European Heart Journal, vol. 39, pp. 3301 - 3310, http://dx.doi.org/10.1093/eurheartj/ehy419
Menon J; Hoeppner VH; Judd A; Power CA; Bretscher PA, 2018, 'A hypothesis for the existence of two types of tuberculosis, reflecting two distinct types of immune failure to control the pathogen, based upon prevalence of mycobacterium-specific IgG subclasses', Scandinavian Journal of Immunology, vol. 87, http://dx.doi.org/10.1111/sji.12665
Norddin N; Power C; Watson G; Cowin G; Kurniawan ND; Gluch L; Bourne RM, 2015, 'Microscopic diffusion properties of fixed breast tissue: Preliminary findings', Magnetic Resonance in Medicine, vol. 74, pp. 1733 - 1739, http://dx.doi.org/10.1002/mrm.25555
Bolton HA; Zhu E; Terry AM; Guy TV; Koh WP; Tan SY; Power CA; Bertolino P; Lahl K; Sparwasser T; Shklovskaya E; Barbara BF, 2015, 'Selective Treg reconstitution during lymphopenia normalizes DC costimulation and prevents graft-versus-host disease', Journal of Clinical Investigation, vol. 125, pp. 3627 - 3641, http://dx.doi.org/10.1172/JCI76031
Thibaudeau L; Taubenberger AV; Holzapfel BM; Quent VM; Fuehrmann T; Hesami P; Brown TD; Dalton PD; Power CA; Hollier BG; Hutmacher DW, 2014, 'A tissue-engineered humanized xenograft model of human breast cancer metastasis to bone', DMM Disease Models and Mechanisms, vol. 7, pp. 299 - 309, http://dx.doi.org/10.1242/dmm.014076
Tse BWC; Jovanovic L; Nelson CC; De Souza P; Power CA; Russell PJ, 2014, 'From Bench to Bedside: Immunotherapy for Prostate Cancer', BioMed Research International, vol. 2014, http://dx.doi.org/10.1155/2014/981434
Bourne R; Power C; Chatterjee A; Cowin G; Kurniawan N; Watson G, 2014, 'DISTINCTIVE WATER DIFFUSION PROPERTIES OF EPITHELIA MAY BE THE KEY TO BETTER CANCER IMAGING TECHNIQUES', ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, vol. 10, pp. 24 - 24, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000344745100056&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Ritchie HE; Ababneh DE; Oakes DJ; Power C; Webster WS, 2013, 'The teratogenic effect of dofetilide during rat limb development and association with drug-induced bradycardia and hypoxia in the embryo', Birth Defects Research Part B - Developmental and Reproductive Toxicology, vol. 98, pp. 144 - 153, http://dx.doi.org/10.1002/bdrb.21050
Holzapfel BM; Thibaudeau L; Power C; Clements J; Russell ; Hutmacher DW, 2013, 'Humanised xenograft models of bone metastasis revisited: Novel insights into species-specific mechanisms of cancer cell osteotropism', Cancer and Metastasis Reviews, vol. 32, pp. 129 - 145, http://dx.doi.org/10.1007/s10555-013-9437-5
Xiao W; Graham PH; Hao J; Chang L; Ni J; Power CA; Dong Q; Kearsley JH; Li Y, 2013, 'Combination Therapy with the Histone Deacetylase Inhibitor LBH589 and Radiation Is an Effective Regimen for Prostate Cancer Cells', PLoS ONE, vol. 8, http://dx.doi.org/10.1371/journal.pone.0074253
Hao J; Madigan MC; Khatri A; Power C; Hung TT; Beretov J; Chang L; Xiao W; Cozzi PJ; Graham PH; Kearsley J; Li Y, 2012, 'In Vitro and In Vivo Prostate Cancer Metastasis and Chemoresistance Can Be Modulated by Expression of either CD44 or CD147', PLoS One, vol. 7, pp. 1 - 14, http://dx.doi.org/10.1371/journal.pone.0040716
Funnell AP; Norton LJ; Mak KS; Burdach J; Artuz CM; Twine NA; Wilkins MR; Power C; Hung TT; Perdomo JS; Bell-Anderson K; Orkin SH; Pearson RC; Crossley M, 2012, 'The CACCC-binding protein KLF3/BKLF represses a subset of KLF1/EKLF target genes and is required for proper erythroid maturation in vivo', Molecular and Cellular Biology, vol. 32, pp. 3281 - 3292, http://dx.doi.org/10.1128/MCB.00173-12
Xiao W; Graham PH; Power C; Hao J; Kearsley J; Li Y, 2012, 'CD44 is a biomarker associated with human prostate cancer radiation sensitivity', Clinical and Experimental Metastasis, vol. 29, pp. 1 - 9, http://dx.doi.org/10.1007/s10585-011-9423-7
Hung TT; Chan J; Russell PJ; Power C, 2011, 'Zoledronic acid preserves bone structure and increases survival but does not limit tumour incidence in a prostate cancer bone metastasis model', PLoS One, vol. 6, pp. 1 - 8, http://dx.doi.org/10.1371/journal.pone.0019389
Tse BW; Russell ; Lochner ; Forster ; Power C, 2011, 'IL-18 inhibits growth of murine orthotopic prostate carcinomas via both adaptive and innate immune mechanisms', PLoS One, vol. 6, pp. e24241, http://dx.doi.org/10.1371/journal.pone.0024241
Wang L; Chen H; Liu F; Madigan MC; Power C; Hao J; Patterson K; Pourgholami MH; O Brien P; Perkins A; Li Y, 2011, 'Monoclonal antibody targeting MUC1 and increasing sensitivity to docetaxel as a novel strategy in treating human epithelial ovarian cancer', Cancer Letters, vol. 300, pp. 122 - 133, http://dx.doi.org/10.1016/j.canlet.2010.09.013
Hao JL; Cozzi PJ; Khatri A; Power CA; Li Y, 2010, 'CD147/EMMPRIN and CD44 are Potential Therapeutic Targets for Metastatic Prostate Cancer', Current Cancer Drug Targets, vol. 10, pp. 287 - 306, http://dx.doi.org/10.2174/156800910791190193
Power C; Marfleet T; Qualtiere L; Xiao W; Bretscher P, 2010, 'Development of Th1 Imprints to rBCG Expressing a Foreign Protein: Implications for Vaccination against HIV-1 and Diverse Influenza Strains', Journal of Biomedicine and Biotechnology, vol. 2010, pp. 1 - 6, http://dx.doi.org/10.1155/2010/591348
Kiros T; Power C; Wei G; Bretscher P, 2010, 'Immunization of newborn and adult mice with low numbers of BCG leads to Th1 responses, Th1 imprints and enhanced protection upon BCG challenge', Immunotherapy, vol. 2, pp. 25 - 35
Li Y; Song YE; Rizvi SM; Power C; Beretov J; Raja C; Cozzi PJ; Morgenstern A; Apostolidis C; Allen BJ; Russell PJ, 2009, 'Inhibition of Micrometastatic Prostate Cancer Cell Spread in Animal Models By (213)Bilabeled Multiple Targeted alpha Radioimmunoconjugates', Clinical Cancer Research, vol. 15, pp. 865 - 875, http://dx.doi.org/10.1158/1078-0432.CCR-08-1203
Power C; Pwint H; Cho J; Yu Y; Walsh W; Russell PJ, 2009, 'A novel model of bone-metastatic prostate cancer in immunocompetent mice', Prostate, vol. 69, pp. 1613 - 1623, http://dx.doi.org/10.1002/pros.21010
Wang J; Rizvi SM; Madigan MC; Cozzi PJ; Power C; Qu CF; Morgenstern A; Apostolidis C; Russell PJ; Allen BJ; Li Y, 2006, 'Control of prostate cancer spheroid growth using 213Bi-labeled multiple targeted alpha radioimmunoconjugates.', Prostate, vol. 66, pp. 1753 - 1767, http://dx.doi.org/10.1002/pros.20502
Power C, 2000, 'Factors that influence T helper cell response to infection', Current Opinion in Infectious Diseases, vol. 13, pp. 209 - 213
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Location

Biological Resources Imaging Lab
Mark Wainwright Analytical Centre
Room 423, Level 4, Lowy Cancer Research Centre
University of New South Wales
Sydney, NSW 2052, Australia


Contact

9385 8655
+61 423 516 571
51720