Research Associate
Facility:
Category: Academic Staff
Research profile: Click to view
Biography
Dr. Ruan started her research career as an electron microscopist. She used electron microscopy to solve the structure of the self-assembled materials during her Ph.D work at Stockholm University. In 2009, she moved into cryo electron microscopy field at Osaka University and dedicated herself to structural biology. She revealed the structure of the flagellar motor of marine bacteria using cryo electron tomography and single particle analysis. In 2018, she moved to UNSW and worked at Electron Microscope Unit. Her research interests focus on the structure and function of biological macromolecular assemblies using single particle analysis, cryo electron tomography and microcrystal electron diffraction.
Publications
Book Chapters
Terasaki O; Ohsuna T; Liu Z; Sakamot Y; Ruan J; Che S, 2007, 'Chapter 14 Structural study of porous materials by electron microscopy', in Introduction to Zeolite Science and Practice, Elsevier, pp. 477 - xiii, http://dx.doi.org/10.1016/s0167-2991(07)80802-0
Terasaki O; Ohsuna T; Liu Z; Sakamoto Y; Ruan J; Che S, 2007, 'Structural Study of Porous Materials by Electron Microscopy', in Studies in Surface Science and Catalysis, Elsevier, pp. 477 - XIII, http://dx.doi.org/10.1016/s0167-2991(07)80802-0
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Journal articles
Huang G; Liu Y; Wang D; Zhu Y; Wen S; Ruan J; Jin D, 2022, 'Upconversion nanoparticles for super-resolution quantification of single small extracellular vesicles', eLight, vol. 2, http://dx.doi.org/10.1186/s43593-022-00031-1
Kuschnerus I; Giri K; Ruan J; Huang Y; Bedford N; Garcia-Bennett A, 2022, 'On the growth of the soft and hard protein corona of mesoporous silica particles with varying morphology', Journal of Colloid and Interface Science, vol. 612, pp. 467 - 478, http://dx.doi.org/10.1016/j.jcis.2021.12.161
Khatib I; Chow MYT; Ruan J; Cipolla D; Chan HK, 2021, 'Modeling of a spray drying method to produce ciprofloxacin nanocrystals inside the liposomes utilizing a response surface methodology: Box-Behnken experimental design', International Journal of Pharmaceutics, vol. 597, pp. 120277 - 120277, http://dx.doi.org/10.1016/j.ijpharm.2021.120277
Wright BW; Ruan J; Molloy MP; Jaschke PR, 2020, 'Genome modularization reveals overlapped gene topology is necessary for efficient viral reproduction', ACS Synthetic Biology, vol. 9, pp. 3079 - 3090, http://dx.doi.org/10.1021/acssynbio.0c00323
Wright BW; Ruan J; Molloy MP; Jaschke PR, 2020, 'Genome modularization reveals overlapped gene topology is necessary for efficient viral reproduction', , http://dx.doi.org/10.1101/2020.06.10.143693
Khanal D; Khatib I; Ruan J; Cipolla D; Dayton F; Blanchard JD; Chan HK; Chrzanowski W, 2020, 'Nanoscale Probing of Liposome Encapsulating Drug Nanocrystal Using Atomic Force Microscopy-Infrared Spectroscopy', Analytical Chemistry, vol. 92, pp. 9922 - 9931, http://dx.doi.org/10.1021/acs.analchem.0c01465
Giri K; Kuschnerus I; Lau M; Ruan J; Garcia-Bennett A, 2020, 'Pore structure and particle shape modulates the protein corona of mesoporous silica particles', Materials Advances, vol. 1, pp. 599 - 603, http://dx.doi.org/10.1039/d0ma00188k
Giri K; Kuschnerus I; Ruan J; Garcia-Bennett AE, 2020, 'Influence of a Protein Corona on the Oral Pharmacokinetics of Testosterone Released from Mesoporous Silica', Advanced Therapeutics, vol. 3, http://dx.doi.org/10.1002/adtp.201900110
Pang B; Zhu Y; Ni J; Ruan J; Thompson J; Malouf D; Bucci J; Graham P; Li Y, 2020, 'Quality assessment and comparison of plasma-derived extracellular vesicles separated by three commercial kits for prostate cancer diagnosis', International Journal of Nanomedicine, vol. 15, pp. 10241 - 10256, http://dx.doi.org/10.2147/IJN.S283106
Khatib I; Tang P; Ruan J; Cipolla D; Dayton F; Blanchard JD; Chan HK, 2020, 'Formation of ciprofloxacin nanocrystals within liposomes by spray drying for controlled release via inhalation', International Journal of Pharmaceutics, vol. 578, pp. 119045 - 119045, http://dx.doi.org/10.1016/j.ijpharm.2020.119045
Kuschnerus I; Lau M; Giri K; Bedford N; Biazik J; Ruan J; Garcia-Bennett A, 2020, 'Effect of a protein corona on the fibrinogen induced cellular oxidative stress of gold nanoparticles', Nanoscale, vol. 12, pp. 5898 - 5905, http://dx.doi.org/10.1039/d0nr00371a
Zhang Q; Mayoral A; Li J; Ruan J; Alfredsson V; Ma Y; Yu J; Terasaki O, 2020, 'Electron Microscopy Studies of Local Structural Modulations in Zeolite Crystals', Angewandte Chemie, http://dx.doi.org/10.1002/ange.202007490
Khatib I; Khanal D; Ruan J; Cipolla D; Dayton F; Blanchard JD; Chan HK, 2019, 'Ciprofloxacin nanocrystals liposomal powders for controlled drug release via inhalation', International Journal of Pharmaceutics, vol. 566, pp. 641 - 651, http://dx.doi.org/10.1016/j.ijpharm.2019.05.068
Berengut JF; Berengut JC; Doye JPK; Prešern D; Kawamoto A; Ruan J; Wainwright MJ; Lee LK, 2019, 'Design and synthesis of pleated DNA origami nanotubes with adjustable diameters', Nucleic Acids Research, vol. 47, pp. 11963 - 11975, http://dx.doi.org/10.1093/nar/gkz1056
Zhang S-D; Petersen N; Zhang W-J; Cargou S; Ruan J; Murat D; Santini C-L; Song T; Kato T; Notareschi P; Li Y; Namba K; Gue A-M; Wu L-F, 2014, 'Swimming behaviour and magnetotaxis function of the marine bacterium strain MO-1', ENVIRONMENTAL MICROBIOLOGY REPORTS, vol. 6, pp. 14 - 20, http://dx.doi.org/10.1111/1758-2229.12102
KATO T; RUAN J, 2014, 'Rotational Mechanism of Hexagonal Seven Flagella Motor at Magnetotactic Bacteria', Seibutsu Butsuri, vol. 54, pp. 024 - 025, http://dx.doi.org/10.2142/biophys.54.024
Ruan J; Kato T; Santini C-L; Wu L-F; Namba K, 2013, '2P157 Structural study of the sheath in the magnetotactic bacterium MO-1 by electron cryomicroscopy(11. Molecular motor,Poster)', Seibutsu Butsuri, vol. 53, pp. S185 - S185, http://dx.doi.org/10.2142/biophys.53.s185_1
Zhang W-J; Santini C-L; Bernadac A; Ruan J; Zhang S-D; Kato T; Li Y; Namba K; Wu L-F, 2012, 'Complex Spatial Organization and Flagellin Composition of Flagellar Propeller from Marine Magnetotactic Ovoid Strain MO-1', JOURNAL OF MOLECULAR BIOLOGY, vol. 416, pp. 558 - 570, http://dx.doi.org/10.1016/j.jmb.2011.12.065
Ruan J; Kjellman T; Sakamoto Y; Alfredsson V, 2012, 'Transient Colloidal Stability Controls the Particle Formation of SBA-15', LANGMUIR, vol. 28, pp. 11567 - 11574, http://dx.doi.org/10.1021/la3013969
Ruan J; Kato T; Santini C-L; Miyata T; Kawamoto A; Zhang W-J; Bernadac A; Wu L-F; Namba K, 2012, 'Architecture of a flagellar apparatus in the fast-swimming magnetotactic bacterium MO-1', PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 109, pp. 20643 - 20648, http://dx.doi.org/10.1073/pnas.1215274109
Zones SI; Ruan J; Elomari S; Terasaki O; Chen CY; Corma A, 2011, 'Studies on zeolite SSZ-57: A structural enigma', SOLID STATE SCIENCES, vol. 13, pp. 706 - 713, http://dx.doi.org/10.1016/j.solidstatesciences.2010.08.004
Ruan J; Kato T; Zhang W-J; Wu L-F; Namba K, 2011, '3M1522 Study of the unique flagellar apparatus of magnetotactic bacteria MO-1 by Electron cryotomography(Molecular motor5,The 49th Annual Meeting of the Biophysical Society of Japan)', Seibutsu Butsuri, vol. 51, pp. S154 - S154, http://dx.doi.org/10.2142/biophys.51.s154_1
Lelis M; Milcius D; Wirth E; Halenius U; Eriksson L; Jansson K; Kadir K; Ruan J; Sato T; Yokosawa T; Noreus D, 2010, 'A mechanically switchable metal-insulator transition in Mg2NiH4 discovers a strain sensitive, nanoscale modulated resistivity connected to a stacking fault', JOURNAL OF ALLOYS AND COMPOUNDS, vol. 496, pp. 81 - 86, http://dx.doi.org/10.1016/j.jallcom.2010.02.135
Ruan J; Kato T; Zhang W-J; Wu L-F; Namba K, 2010, '3P147 Structural study of the flagellar bundle of magnetotactic bacterium MO-1 by electron cryotomography(Molecular motor,The 48th Annual Meeting of the Biophysical Society of Japan)', Seibutsu Butsuri, vol. 50, pp. S170 - S171, http://dx.doi.org/10.2142/biophys.50.s170_6
Gao C; Izquierdo-Barba I; Nakase I; Futaki S; Ruan J; Sakamoto K; Sakamoto Y; Kuroda K; Terasaki O; Che S, 2009, 'Mesostructured silica based delivery system for a drug with a peptide as a cell-penetrating vector', MICROPOROUS AND MESOPOROUS MATERIALS, vol. 122, pp. 201 - 207, http://dx.doi.org/10.1016/j.micromeso.2009.03.002
Sakamoto S; Shimojima A; Miyasaka K; Ruan J; Terasaki O; Kuroda K, 2009, 'Formation of Two- and Three-Dimensional Hybrid Mesostructures from Branched Siloxane Molecules', JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 131, pp. 9634 - 9635, http://dx.doi.org/10.1021/ja903176k
Ruan J; Wu P; Slater B; Zhao Z; Wu L; Terasaki O, 2009, 'Structural Characterization of Interlayer Expanded Zeolite Prepared From Ferrierite Lamellar Precursor', CHEMISTRY OF MATERIALS, vol. 21, pp. 2904 - 2911, http://dx.doi.org/10.1021/cm900645c
Shu P; Ruan J; Gao C; Li H; Che S, 2009, 'Formation of mesoporous Co3O4 replicas of different mesostructures with different pore sizes', MICROPOROUS AND MESOPOROUS MATERIALS, vol. 123, pp. 314 - 323, http://dx.doi.org/10.1016/j.micromeso.2009.04.017
Fan C; Qiu H; Ruan J; Terasaki O; Yan Y; Wei Z; Che S, 2008, 'Formation of Chiral Mesopores in Conducting Polymers by Chiral-Lipid-Ribbon Templating and "Seeding" Route', ADVANCED FUNCTIONAL MATERIALS, vol. 18, pp. 2699 - 2707, http://dx.doi.org/10.1002/adfm.200701456
Wu P; Ruan J; Wang L; Wu L; Wang Y; Liu Y; Fan W; He M; Terasaki O; Tatsumi T, 2008, 'Methodology for synthesizing crystalline metallosilicates with expanded pore windows through molecular alkoxysilylation of zeolitic lamellar precursors', JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 130, pp. 8178 - 8187, http://dx.doi.org/10.1021/ja0758739
Han L; Ruan J; Li Y; Terasaki O; Che S, 2007, 'Synthesis and characterization of the amphoteric amino acid bifunctional mesoporous silica', CHEMISTRY OF MATERIALS, vol. 19, pp. 2860 - 2867, http://dx.doi.org/10.1021/cm0705845
Wu X; Ruan J; Ohsuna T; Terasaki O; Che S, 2007, 'A novel route for synthesizing silica nanotubes with chiral mesoporous wall structures', CHEMISTRY OF MATERIALS, vol. 19, pp. 1577 - 1583, http://dx.doi.org/10.1021/cm062368m
Ruan JF; Wu P; Slater B; Terasaki O, 2005, 'Structure elucidation of the highly active titanosilicate catalyst Ti-YNU-1', ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. 44, pp. 6719 - 6723, http://dx.doi.org/10.1002/anie.200501939
Ruan J; Wu P; Slater B; Terasaki O, 2005, 'Structure Elucidation of the Highly Active Titanosilicate Catalyst Ti-YNU-1', Angewandte Chemie, vol. 117, pp. 6877 - 6881, http://dx.doi.org/10.1002/ange.200501939
Ruan JF; Kuo KH; Guo JQ; Tsai AP, 2004, 'Crystalline phases displaying pseudo-icosahedral symmetry in Ag42In42RE16 (RE = Gd, Tb, Dy, Ho, Er, Tm, Yb, and Lu)', JOURNAL OF ALLOYS AND COMPOUNDS, vol. 370, pp. L23 - L27, http://dx.doi.org/10.1016/j.jallcom.2003.09.111
Wu P; Nuntasri D; Ruan JF; Liu YM; He MY; Fan WB; Terasaki O; Tatsumi T, 2004, 'Delamination of Ti-MWW and high efficiency in epoxidation of alkenes with various molecular sizes', JOURNAL OF PHYSICAL CHEMISTRY B, vol. 108, pp. 19126 - 19131, http://dx.doi.org/10.1021/jp037459a
Preprints
Dickson CF; Hertel S; Ruan J; Ariotti N; Tuckwell A; Li N; Al-Izzi SC; Sierecki E; Gambin Y; Morris RG; Towers GJ; Böcking T; Jacques DA, 2023, Karyopherin mimicry explains how the HIV capsid penetrates nuclear pores, http://dx.doi.org/10.1101/2023.03.23.534032
Kuschnerus IC; Wen H; Khine YY; Ruan J; Su C-J; Jeng U-S; Opletal G; Barnard A; Osawa E; Shenderova O; Mochalin V; Liu M; Nishikawa M; Chang SLY, 2022, Fabrication Process Independent and Robust Aggregation Formation of Detonation Nanodiamonds in Aqueous Media, http://dx.doi.org/10.2139/ssrn.4049511
Berengut JF; Ruan J; Kawamoto A; Lee LK, 2019, Design and Synthesis of Pleated DNA Origami Nanotubes with Adjustable Diameters, http://dx.doi.org/10.1101/534792
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Location
Room G35, Ground, Chemical Sciences Building (F10), Kensington Campus
