Research Associate
Facility:
Category: Academic Staff
Research profile: Click to view
Biography
Dr. Ruan started her research career as an electron microscopist. She used electron microscopy to solve the structure of the self-assembled materials during her Ph.D work at Stockholm University. In 2009, she moved into cryo electron microscopy field at Osaka University and dedicated herself to structural biology. She revealed the structure of the flagellar motor of marine bacteria using cryo electron tomography and single particle analysis. In 2018, she moved to UNSW and worked at Electron Microscope Unit. Her research interests focus on the structure and function of biological macromolecular assemblies using single particle analysis, cryo electron tomography and microcrystal electron diffraction.
Publications
Book Chapters
, 2007, 'Chapter 14 Structural study of porous materials by electron microscopy', in Introduction to Zeolite Science and Practice, Elsevier, pp. 477 - xiii, http://dx.doi.org/10.1016/s0167-2991(07)80802-0
, 2007, 'Structural Study of Porous Materials by Electron Microscopy', in Studies in Surface Science and Catalysis, Elsevier, pp. 477 - XIII, http://dx.doi.org/10.1016/s0167-2991(07)80802-0
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Journal articles
, 2024, 'The HIV capsid mimics karyopherin engagement of FG-nucleoporins', Nature, 626, pp. 836 - 842, http://dx.doi.org/10.1038/s41586-023-06969-7
, 2023, 'Fabrication process independent and robust aggregation of detonation nanodiamonds in aqueous media', Diamond and Related Materials, 139, http://dx.doi.org/10.1016/j.diamond.2023.110199
, 2023, 'Hierarchical assembly of tryptophan zipper peptides into stress-relaxing bioactive hydrogels', Nature Communications, 14, http://dx.doi.org/10.1038/s41467-023-41907-1
, 2023, 'Insight into Bioactivity of In‐situ Trapped Enzyme‐Covalent‐Organic Frameworks', Angewandte Chemie, 135, http://dx.doi.org/10.1002/ange.202303001
, 2023, 'Insight into Bioactivity of In-situ Trapped Enzyme-Covalent-Organic Frameworks', Angewandte Chemie - International Edition, 62, pp. e202303001, http://dx.doi.org/10.1002/anie.202303001
, 2023, 'Complex Dispersion of Detonation Nanodiamond Revealed by Machine Learning Assisted Cryo-TEM and Coarse-Grained Molecular Dynamics Simulations', ACS Nanoscience Au, 3, pp. 211 - 221, http://dx.doi.org/10.1021/acsnanoscienceau.2c00055
, 2022, 'Upconversion nanoparticles for super-resolution quantification of single small extracellular vesicles', eLight, 2, http://dx.doi.org/10.1186/s43593-022-00031-1
, 2022, 'On the growth of the soft and hard protein corona of mesoporous silica particles with varying morphology', Journal of Colloid and Interface Science, 612, pp. 467 - 478, http://dx.doi.org/10.1016/j.jcis.2021.12.161
, 2021, 'Modeling of a spray drying method to produce ciprofloxacin nanocrystals inside the liposomes utilizing a response surface methodology: Box-Behnken experimental design', International Journal of Pharmaceutics, 597, http://dx.doi.org/10.1016/j.ijpharm.2021.120277
, 2020, 'Formation of ciprofloxacin nanocrystals within liposomes by spray drying for controlled release via inhalation', International Journal of Pharmaceutics, 578, http://dx.doi.org/10.1016/j.ijpharm.2020.119045
, 2020, 'Genome modularization reveals overlapped gene topology is necessary for efficient viral reproduction', ACS Synthetic Biology, 9, pp. 3079 - 3090, http://dx.doi.org/10.1021/acssynbio.0c00323
, 2020, 'Genome modularization reveals overlapped gene topology is necessary for efficient viral reproduction', , http://dx.doi.org/10.1101/2020.06.10.143693
, 2020, 'Nanoscale Probing of Liposome Encapsulating Drug Nanocrystal Using Atomic Force Microscopy-Infrared Spectroscopy', Analytical Chemistry, 92, pp. 9922 - 9931, http://dx.doi.org/10.1021/acs.analchem.0c01465
, 2020, 'Pore structure and particle shape modulates the protein corona of mesoporous silica particles', Materials Advances, 1, pp. 599 - 603, http://dx.doi.org/10.1039/d0ma00188k
, 2020, 'Influence of a Protein Corona on the Oral Pharmacokinetics of Testosterone Released from Mesoporous Silica', Advanced Therapeutics, 3, http://dx.doi.org/10.1002/adtp.201900110
, 2020, 'Quality assessment and comparison of plasma-derived extracellular vesicles separated by three commercial kits for prostate cancer diagnosis', International Journal of Nanomedicine, 15, pp. 10241 - 10256, http://dx.doi.org/10.2147/IJN.S283106
, 2020, 'Effect of a protein corona on the fibrinogen induced cellular oxidative stress of gold nanoparticles', Nanoscale, 12, pp. 5898 - 5905, http://dx.doi.org/10.1039/d0nr00371a
, 2020, 'Electron Microscopy Studies of Local Structural Modulations in Zeolite Crystals', Angewandte Chemie, http://dx.doi.org/10.1002/ange.202007490
, 2019, 'Ciprofloxacin nanocrystals liposomal powders for controlled drug release via inhalation', International Journal of Pharmaceutics, 566, pp. 641 - 651, http://dx.doi.org/10.1016/j.ijpharm.2019.05.068
, 2019, 'Design and synthesis of pleated DNA origami nanotubes with adjustable diameters', Nucleic Acids Research, 47, pp. 11963 - 11975, http://dx.doi.org/10.1093/nar/gkz1056
, 2014, 'Swimming behaviour and magnetotaxis function of the marine bacterium strain MO-1', ENVIRONMENTAL MICROBIOLOGY REPORTS, 6, pp. 14 - 20, http://dx.doi.org/10.1111/1758-2229.12102
, 2014, 'Rotational Mechanism of Hexagonal Seven Flagella Motor at Magnetotactic Bacteria', Seibutsu Butsuri, 54, pp. 024 - 025, http://dx.doi.org/10.2142/biophys.54.024
, 2013, '2P157 Structural study of the sheath in the magnetotactic bacterium MO-1 by electron cryomicroscopy(11. Molecular motor,Poster)', Seibutsu Butsuri, 53, pp. S185 - S185, http://dx.doi.org/10.2142/biophys.53.s185_1
, 2012, 'Architecture of a flagellar apparatus in the fast-swimming magnetotactic bacterium MO-1', PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 109, pp. 20643 - 20648, http://dx.doi.org/10.1073/pnas.1215274109
, 2012, 'Transient Colloidal Stability Controls the Particle Formation of SBA-15', LANGMUIR, 28, pp. 11567 - 11574, http://dx.doi.org/10.1021/la3013969
, 2012, 'Complex Spatial Organization and Flagellin Composition of Flagellar Propeller from Marine Magnetotactic Ovoid Strain MO-1', JOURNAL OF MOLECULAR BIOLOGY, 416, pp. 558 - 570, http://dx.doi.org/10.1016/j.jmb.2011.12.065
, 2011, 'Studies on zeolite SSZ-57: A structural enigma', SOLID STATE SCIENCES, 13, pp. 706 - 713, http://dx.doi.org/10.1016/j.solidstatesciences.2010.08.004
, 2011, '3M1522 Study of the unique flagellar apparatus of magnetotactic bacteria MO-1 by Electron cryotomography(Molecular motor5,The 49th Annual Meeting of the Biophysical Society of Japan)', Seibutsu Butsuri, 51, pp. S154 - S154, http://dx.doi.org/10.2142/biophys.51.s154_1
, 2010, 'A mechanically switchable metal-insulator transition in Mg2NiH4 discovers a strain sensitive, nanoscale modulated resistivity connected to a stacking fault', JOURNAL OF ALLOYS AND COMPOUNDS, 496, pp. 81 - 86, http://dx.doi.org/10.1016/j.jallcom.2010.02.135
, 2010, '3P147 Structural study of the flagellar bundle of magnetotactic bacterium MO-1 by electron cryotomography(Molecular motor,The 48th Annual Meeting of the Biophysical Society of Japan)', Seibutsu Butsuri, 50, pp. S170 - S171, http://dx.doi.org/10.2142/biophys.50.s170_6
, 2009, 'Formation of Two- and Three-Dimensional Hybrid Mesostructures from Branched Siloxane Molecules', JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 131, pp. 9634 - 9635, http://dx.doi.org/10.1021/ja903176k
, 2009, 'Mesostructured silica based delivery system for a drug with a peptide as a cell-penetrating vector', MICROPOROUS AND MESOPOROUS MATERIALS, 122, pp. 201 - 207, http://dx.doi.org/10.1016/j.micromeso.2009.03.002
, 2009, 'Structural Characterization of Interlayer Expanded Zeolite Prepared From Ferrierite Lamellar Precursor', CHEMISTRY OF MATERIALS, 21, pp. 2904 - 2911, http://dx.doi.org/10.1021/cm900645c
, 2009, 'Formation of mesoporous Co3O4 replicas of different mesostructures with different pore sizes', MICROPOROUS AND MESOPOROUS MATERIALS, 123, pp. 314 - 323, http://dx.doi.org/10.1016/j.micromeso.2009.04.017
, 2008, 'Methodology for synthesizing crystalline metallosilicates with expanded pore windows through molecular alkoxysilylation of zeolitic lamellar precursors', JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 130, pp. 8178 - 8187, http://dx.doi.org/10.1021/ja0758739
, 2008, 'Formation of Chiral Mesopores in Conducting Polymers by Chiral-Lipid-Ribbon Templating and "Seeding" Route', ADVANCED FUNCTIONAL MATERIALS, 18, pp. 2699 - 2707, http://dx.doi.org/10.1002/adfm.200701456
, 2007, 'Synthesis and characterization of the amphoteric amino acid bifunctional mesoporous silica', CHEMISTRY OF MATERIALS, 19, pp. 2860 - 2867, http://dx.doi.org/10.1021/cm0705845
, 2007, 'A novel route for synthesizing silica nanotubes with chiral mesoporous wall structures', CHEMISTRY OF MATERIALS, 19, pp. 1577 - 1583, http://dx.doi.org/10.1021/cm062368m
, 2005, 'Structure elucidation of the highly active titanosilicate catalyst Ti-YNU-1', ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 44, pp. 6719 - 6723, http://dx.doi.org/10.1002/anie.200501939
, 2005, 'Structure Elucidation of the Highly Active Titanosilicate Catalyst Ti‐YNU‐1', Angewandte Chemie, 117, pp. 6877 - 6881, http://dx.doi.org/10.1002/ange.200501939
, 2004, 'Delamination of Ti-MWW and high efficiency in epoxidation of alkenes with various molecular sizes', JOURNAL OF PHYSICAL CHEMISTRY B, 108, pp. 19126 - 19131, http://dx.doi.org/10.1021/jp037459a
, 2004, 'Crystalline phases displaying pseudo-icosahedral symmetry in Ag42In42RE16 (RE = Gd, Tb, Dy, Ho, Er, Tm, Yb, and Lu)', JOURNAL OF ALLOYS AND COMPOUNDS, 370, pp. L23 - L27, http://dx.doi.org/10.1016/j.jallcom.2003.09.111
Preprints
, 2024, Molecular basis for the assembly of the Vps5-Vps17 SNX-BAR proteins with Retromer, , http://dx.doi.org/10.1101/2024.03.24.586500
, 2023, Karyopherin mimicry explains how the HIV capsid penetrates nuclear pores, , http://dx.doi.org/10.1101/2023.03.23.534032
, 2022, Precision super-resolution cryo-correlative light and electron microscopy for rapidin situstructural analyses of optogenetically-positioned organelles, , http://dx.doi.org/10.1101/2022.11.22.516823
, 2019, Design and Synthesis of Pleated DNA Origami Nanotubes with Adjustable Diameters, , http://dx.doi.org/10.1101/534792
, Fabrication Process Independent and Robust Aggregation Formation of Detonation Nanodiamonds in Aqueous Media, , http://dx.doi.org/10.2139/ssrn.4049511
, Precision Super-Resolution Cryo-Correlative Light and Electron Microscopy for Rapid <i>in situ</i> Structural Analyses of Optogenetically-Positioned Organelles, , http://dx.doi.org/10.2139/ssrn.4309027
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Location
Room G35, Ground, Chemical Sciences Building (F10), Kensington Campus
