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Empyrean 1 (PANalytical) Thin-Film XRD

The Empyrean Thin-Film XRD installed in 2013, provides thin-film analysis or BB geometry with variable temperature stages and reaction cell for in situ studies.

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Empyrean 2 (PANalytical) X-ray Diffraction System (Cobalt)

The Empyrean 2 is a Bragg-Brentano geometry X-ray diffractometer that was installed in 2014 and is equipped with the following components:

  • Cobalt anode X-ray tube to minimise fluorescence from iron-containing samples that occurs when using the standard copper X-ray anode
  • High resolution optic for cobalt X-rays to minimise scatter at low angles
  • Sample changer for large batches 

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Empyrean 3 (PANalytical) XRD with Ag source and PSD

The Empyrean 3 is fitted with a silver source and a position-sensitive detector to instantly capture a wide 2-theta angular range during an in situ XRD experiment without the need to scan the detector. The instrument can run capillary samples and the high energy silver source also enables the instrument to perform the pair distribution function (PDF) experiment that describes the distribution of distances between pairs of atoms within a material.

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EMU Specimen Preparation Equipment

The EMU specimen preparation suite includes equipment designed for specimen preparation for microscopy, in addition to basic lab equipment. For training or access to any of these pieces of equipment, please speak to EMU staff.

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Energy Dispersive X-ray Fluorescence Spectrometers

The Malvern-PANalytical Epsilon Energy Dispersive X-ray fluorescence spectrometer (ED-XRF) was installed as a demonstration instrument in 2018. It is a state-of-the-art ED-XRF with sample changer and is capable of analysing sodium through to uranium. Data can be optionally processed via full fundamental parameter model and Compton ratio correction, and a standardless program for metal analysis is available.

The Lab also has an Olympus portable ED-XRF suitable for chemical analysis of large samples or in the field.

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EPMA - JEOL JXA-8500F Field-Emission SEM-EPMA Hyperprobe (WDS & SDD-EDS)

EPMA - JEOL JXA-8500F Field-Emission SEM-EPMA Hyperprobe (WDS & SDD-EDS)

The JEOL JXA-8500F is a powerful microanalytical instrument that provides area-specific quantitative elemental results down to the sub-micron level. The electron probe microanalyser (EPMA) is fitted with four wavelength dispersive spectrometers (WDS) and a JEOL silicon drift detector energy dispersive spectrometer (SDD-EDS), giving this instrument the capability to detect and measure the concentration of most elements in the periodic table Z=4), with detection limits often better than <0.05%.

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Faxitron MX-20

Faxitron MX-20

The Faxitron MX-20 is a self contained bench-top x-ray cabinet which produces digital 2D radiographs in either png or jpg file formats. It has 5 magnification levels and laser guide for sample alignment.

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FIB - Carl Zeiss AURIGA® CrossBeam® Workstation

FIB - Carl Zeiss AURIGA® CrossBeam® Workstation

The Carl Zeiss AURIGA® CrossBeam® Workstation (installed in 2011) is a sophisticated multi-functional platform based on a high performance field emission scanning electron microscope (FESEM) combined with a powerful focused ion beam (FIB) system operating in the analogue mode. It is equipped with an advanced Oxford Instruments’ X-Max large area (20mm2) silicon drift detector (SDD) energy dispersive spectrometer (EDS) and a super high speed NordlysF detector electron back-scattered diffraction (EBSD) analytical system.

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FIB - FEI Nova Nanolab 200

FIB - FEI Nova Nanolab 200

The FEI xT Nova NanoLab 200 combines a high resolution focussed ion beam (FIB) and a high resolution field emission scanning electron microscope (FESEM). It was installed in 2004 and is a flagship instrument of Australian Microscopy and Microanalysis Research Facility (AMMRF).  It was upgraded to PIA mode in 2011 for higher precision of ion milling on a new operating system.

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Flow Cytometry

Flow Cytometry

Flow Cytometry is a technology that simultaneously measures and analyses multiple physical characteristics of single particles, usually cells, as they flow in a fluid stream through a beam of light. The properties measured include a particle’s relative size, relative granularity or internal complexity, and relative fluorescence intensity. These characteristics are determined using an optical-to-electronic coupling system that records how the cell or particle scatters incident laser light and emits fluorescence.

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FluoView FV1200

FluoView FV1200

The FV1200 is a filter based upright confocal system. A workhorse of our confocal systems it is well equipped for standard fixed samples where high resolution and sensitivity are required for localization based studies. Additionally as one of the few upright confocal systems within the BMIF it provides a means for visualizing water submerged opaque samples.

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Gas Chromatography

Gas Chromatography

Chromatography is the separation of a mixture of compounds (solutes) into separate components. By separating the sample into individual components, it is easier to identify (qualitative) and measure the amount (quantitate) of the various sample components. There are numerous chromatographic techniques and corresponding instruments. Gas chromatography (GC) is one of these techniques. It is estimated that 10-20% of the known compounds can be analysed by GC.

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Gas Chromatography / Mass Spectrometry

Low Molecular Weight: Analysis of Small Molecules including Metabolomic Analysis

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GE and BioRad mini and large format SDS-PAGE systems

Proteomic work can involve the use of two-dimensional polyacrylamide gel electrophoresis (2-D PAGE or 2-DE). In 2-DE, "first dimension" electrophoresis in a polyacrylamide gel with a pH gradient and high urea concentration is followed by a "second dimension" separation in an SDS-PAGE gel. SDS-PAGE can also be used independently. Proteins and peptides are separated within the gel according to the % acrylamide and crosslinker, given as %T and %C.

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GE Healthcare iTC200 Isothermal Calorimeter

Investigating molecular interactions, reaction kinetics and thermodynamics by Isothermal Calorimeter (iTC). Production or absorption of heat is a universal event consequent to the binding of two molecules or a chemical reaction. iTC is the only equipment that can directly measure the energetics of biochemical processes involving interaction between two molecules such as a receptor and a ligand.

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GE IPGphor/Multiphor Isoelectric Focusing Systems

Isoelectric focusing (IEF) systems are used for: the fractionation of complex biological samples in pathway and systems analysis; quantitation of protein effector molecules; elucidation of protein modifications; and sample clean-up for ongoing analysis. It is used in conjunction with immobilised pH gradients of length 7cm, 13cm, or 18cm for broad range pH3-10, mid range pH4-7, 6-11, or narrow range with 0.01pH unit separating power.

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In vivo Imaging

In vivo Imaging

BRIL imaging technologies encompasses current major in vivo imaging modalities such as high frequency ultrasound, positron emission tomography (PET), micro computed tomography (microCT), and optical imaging (bioluminescence and fluorescence). The data from imaging platforms such as microPET-CT and ultrasound can have maximal clinical relevance, allowing quick bench-to-bedside technology transfer.

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IncuCyte FLR

IncuCyte FLR

The IncuCyte FLR is a widefield inverted live cell system engineered with long term high throughput imaging in mind. Housed inside a tissue culture incubator, the imaging module maintains the most stable imaging conditions possible, and also comes with a selection of versatile inserts allowing you to imagine your cells in a range of vessels.

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Inveon MicroPET-CT

Inveon MicroPET-CT

The Inveon μCT uses multiple axial x-rays of the animal to generate cross-sectional information or 3-dimensional reconstructions of the animal or parts of the animal. The μPET uses an LSO detector for fast scintillation decay time, high light output and effective atomic number.

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IVIS Lumina and IVIS SpectrumCT

IVIS Lumina and IVIS SpectrumCT

The IVIS Lumina provides a highly sensitive means to image fluorescent and/or bioluminescent reporters in vivo and in vitro. The IVIS SpectrumCT expands upon optical imaging capabilities as well as providing a microCT capability for anatomical referencing.

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