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Inveon MicroPET-CT

Inveon MicroPET-CT

The Inveon μCT uses multiple axial x-rays of the animal to generate cross-sectional information or 3-dimensional reconstructions of the animal or parts of the animal. The μPET uses an LSO detector for fast scintillation decay time, high light output and effective atomic number.

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IVIS Lumina and IVIS SpectrumCT

IVIS Lumina and IVIS SpectrumCT

The IVIS Lumina provides a highly sensitive means to image fluorescent and/or bioluminescent reporters in vivo and in vitro. The IVIS SpectrumCT expands upon optical imaging capabilities as well as providing a microCT capability for anatomical referencing.

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JEOL 7001F FE-SEM

The JEOL 7001F is a Schottky field emission scanning electron microscope. The Schottky field emission electron gun produces a very finely focused, high current electron beam suitable for specialist high resolution microstructural analysis of inorganic materials. The "below lens" configured 7001F can accommodate specimens of up to 25mm in diameter, but specimen tilt is restricted because of the presence of a number of specialist microanalytical detectors within the specimen chamber.

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JEOL JEM-F200 Multi-Purpose FEG-S/TEM

JEOL JEM-F200 Multi-Purpose FEG-S/TEM

The JEOL JEM-F200 (installed in 2017) is a cold field emission gun (FEG) scanning transmission electron microscope (S/TEM) that operates at 200 kV (with an option of opearating at 80 kV under special request). The high brightness and coherence of the cold FEG mean that this microscope is ideally suited for analytical microscopy of materials. The F200 has a lattice resolution of 0.16 nm in ADF STEM mode and 0.1 nm in TEM mode at 200 kV.

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JEOL JSPM 5400 MkII Environmental Atomic Force Microscope

JEOL JSPM 5400 MkII is an environmental Scanning Probe Microscope which is configured for observation and nano-characterisation of inorganic and device materials. The JEOL JSPM 5400 MkII eAFM has a number of piezo-scanners and a range of atomic force imaging modes which may be operated in ambient and high vacuum conditions (~10-6 Pa) enabling control of environmental conditions (pressure and temperature) during imaging. Some examples of the imaging modes available include contact, intermittent contact and non-contact topography imaging.

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JEOL JXA-8500F Field-Emission SEM-EPMA Hyperprobe (WDS & SDD-EDS)

JEOL JXA-8500F Field-Emission SEM-EPMA Hyperprobe (WDS & SDD-EDS)

The JEOL JXA-8500F is a powerful microanalytical instrument that provides area-specific quantitative elemental results down to the sub-micron level. The electron probe microanalyser (EPMA) is fitted with four wavelength dispersive spectrometers (WDS) and a JEOL silicon drift detector energy dispersive spectrometer (SDD-EDS), giving this instrument the capability to detect and measure the concentration of most elements in the periodic table Z=4), with detection limits often better than <0.05%.

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JEOL TEM-1400

JEOL TEM-1400

The JEOL 1400 transmission electron microscope operates at accelerating voltages up to 120kV. The microscope is equipped with a high contrast lens configuration especially suited to imaging biological, medical or polymer specimens that lack electron density and inherent contrast. Specimens undergo preparation procedures to ensure they are 100 nm or thinner in order to transmit the electron beam. Dense regions within the specimen cause electrons to scatter and an aperture, positioned near the specimen in the electron column, prevents the scattered electrons from reaching the imaging plane.

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Lavision TriM Scope II Multiphoton Intravital

Lavision TriM Scope II Multiphoton Intravital

This intravital microscope boasts an impressive collection of hardware. Equipped with 2 multiphoton lasers utilising a pre-chirp compensator to keep laser pulse width < 150 fs, a collection of detectors including high sensitive NDD detectors close to the objective lens, descanned PMTs, imaging cameras for fast 64 beam scanning and also LaVision BioTec's FLIM x16 TCSPC detector for rappid fluorescence lifetime measurements. 

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Leica 165C Microscope

The Leica microscope has a large working distance between the objective and sample and an incident cold light source to enable our crystallographers to mount single-crystals onto a capillary, prior to measuring the diffraction pattern. Images and dimensions of a crystal can be collected using the CCD camera. When not in use by our crystallographers, the microscope may be used, at no cost, by UNSW researchers who require a low to medium magnification (max.90x) digital image of their sample.

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Leica DM IL

Leica DM IL

The Leica DM IL microscope is used to illuminate whole cells; observing and analysing a cell as a single entity. The DM IL is an inverted epifluorescence microscope, with transmitted light LED back illumination and an EL6000 Fluoro system.

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Leica RM2135 Rotary Microtome

Leica RM2135 Rotary Microtome

Leica RM2135 rotary microtome is used to cut very thin cross-sections of specimens (usually 4 µm) for routine and research histology studies in the fields of biology and medicine.  This instrument is designed for cutting soft and harder paraffin embedded specimens, as long as they are suitable for being cut manually.  The sectioning thickness setting range can be from 1 µm to 60 µm.  High quality paraffin sections could be used for varying staining, such as Haematoxylin and Eosin stain (H&E), immunohistochemistry (IHC), Immunofluorescent staining (IF) and In situ hybridization (ISH).

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Leica SP8 DLS

Leica SP8 DLS

The Leica TCS SP8 DLS (Digital LightSheet) is an inverted laser scanning microscope capable to be used for confocal imaging and light sheet imaging. This microscope is able to image multi-colour, live, fixed or aqueous-based cleared specimens utilising a combinations of 405, 458, 488, 514, 561 and 635 nm excitation lasers through the employment of the AOBS with spectral high quantum efficiency detectors. The advantage of the two combined features (confocal/Lightsheet) on a single equipment allow to perform, with the confocal module, local photo activation or photo bleaching where the resulting dynamics can be capture via lightsheet imaging on thick sample (up to 2 mm thick and 1 cm long).

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Leica TCS SP5 MP STED

Leica TCS SP5 MP STED

Leica TCS SP5 equipped with a Spectra-Physics Mai Tai Ti:Sapphire laser is an inverted confocal laser scanning microscope. It is designed for high-resolution fluorescence and transmitted light imaging with single or multi-photon excitation, in 2D, 3D or 4D with live or fixed cells. It can also be used for Fluorescence Recovery After Photo bleaching (FRAP), pulsed Stimulated Emission Depletion (pulsed STED) and Fluorescence Correlation Spectroscopy (FCS). In combination with the Picoquant Microtime200, it can be used for Fluorescence Correlation Spectroscopy (FCS) coupled to Fluorescence Lifetime Imaging (FLIM).

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Leica TCS SP5 WLL STED

Leica TCS SP5 WLL STED

This Leica TCS SP5 confocal system is equipped for a broad range of experimental requirements. Along with a range of fixed wavelength laser lines it now has a White-Light Laser (WLL) tunable within the range x-x for precise control over fluorophore excitation. Fitted with Hybrid Dectors (HyD) for enhanced sensitivity, and interchangeable Galvano and resonant scanners, this system is suitable for applications requiring both speed and/or improved signal-to-noise. Its Gated-STED module also enables colleciton of super-resolution images allowing investigators to distinguish objects and structures beyond the conventional resolution limit of light.

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Liquid Chromatography

Separation and Fractionation

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Liquid Chromatography / Mass Spectrometry

Proteins, Polymers and other High MW or Polar Molecules including Proteomics

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Matrix Assisted Laser Desorption / Ionisation

Proteins, Polymers and other High MW or Polar Molecules including Proteomics

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MPD (PANalytical) Xpert Multipurpose X-ray Diffraction System

The MPD is a Bragg-Brentano geometry X-ray diffractometer suitable for routine measurement of powder samples, either phase identification or quantitative analysis. The instrument is equipped with the following components:

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MRD (PANalytical) Xpert Materials Research diffractometer

The MRD is a highly flexible X-ray diffraction system, equipped with X-ray mirror, (220) Ge monochromator, X-ray lens, mono-capillary, triple-axis goniometer, and is used for analysis of thin films, nanostructure, semiconductor materials, stresses and textures. It is equipped with a few active components, such as an X-ray mirror, Ge 220 monochromator, X-ray lens and mono-capillary for incident beam conditioning, and parallel plate collimator or triple-axis for diffracted beam conditioning. Both proportional and area detectors are available.

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Multispectral Optoacoustic Tomography

Multispectral Optoacoustic Tomography

Optoacoustic or photoacoustic imaging is a new, cutting-edge imaging technique which detects ultrasound waves following light absorption from specific molecules.  This technique allows molecules with different spectral profile to be detected.

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Muromachi Microwave Fixation System

Muromachi Microwave Fixation System

The Muromachi microwave fixation system offers an effective way to inactivate these enzymes in the intact specimen.

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NanoSight NS300

NanoSight NS300

The NanoSight NS300 utilizes the latest version of NanoSight’s particle characterization technology, Nanoparticle Tracking Analysis (NTA). This elegant new instrument offers the unique benefits scientists have come to expect from NanoSight in a compact format, with the major benefit of enhanced fluorescence capability.

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Nikon A1 Intravital

Nikon A1 Intravital

The Nikon A1 intravital microscope is an inverted confocal system designed for fast stable imaging over time. With two scanners, a standard Galvano scanner for achieving images with a high signal-to-noise ratio and a resonant scanner for when speed is of upmost importance, this system is suitable for a wide range of experiments. Equipped with 4 dedicated PMTs for reflective/fluorescence imaging, 2 of which as high efficiency GaAsP detectors, and a hardware solution (Perfect Focus System) for preventing drift during imaging this system yields both high sensitiy with speed and stability. 

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